Molecular Mechanisms of Embryonic Stem Cell Pluripotency ( Pluripotent Stem Cells )

Publication series ： Pluripotent Stem Cells

Author： Guofeng Han Hongtao Wang and Jijun Hao  

Publisher： IntechOpen‎

Publication year： 2013

E-ISBN: INT4591754365

P-ISBN(Paperback): 9789535111924

P-ISBN(Hardback):  9789535111924

Subject： Q2 Cytobiology

Keyword： 细胞生物学

Language： ENG

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Molecular Mechanisms of Embryonic Stem Cell Pluripotency

Chapter

Chapter 13 Molecular Mechanisms of Embryonic Stem Cell Pluripotency

1. Introduction

2. Signaling pathways of ES cells

2.1. LIF/JAK/STAT3 pathway

2.2. TGF-β signaling

2.2.1. BMP signaling pathway

2.2.2. TGF-β/activin/nodal signaling pathway

2.2.3. Growth and Differentiation factor 3 (GDF-3)

2.3. FGF/MEK signaling

3. The regulatory network of pluripotency factors

3.1. OCT4 and SOX2

3.2. Nanog

4. Summary

Author details

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