Telomeres: Biological Functions, Sequencing and Aging
( Genetics - Research and Issues )
Publication series ：Genetics - Research and Issues
Author： Nicolás E. Dominguez and Sofia M. Pereyra
Publisher： Nova Science Publishers, Inc.
Publication year： 2012
E-ISBN: 9781619426375
Subject： Q343.2 chromosome genetics theory (chromosome)
Keyword： Genetics
Language： ENG
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Description
Telomere is the nucleoprotein complex located at the endmost chromosomal terminus and one of the essential cis-acting structural elements of chromosomes. Telomeres are composed of DNA, proteins, and RNA. In this book, the authors present current research in the study of the biological functions, sequencing and ageing of telomeres. Topics discussed include the biology of telomeres in multipotential stromal cells; telomere maintenance in the blight fungus ustilago maydis; telomere length in lymphoid malignancies; unravelling the genetic basis of the alternative lengthening of telomeres; and, the adjustment of telomeres by cell-matrix interaction.