Biophysics of DNA-Antibiotic Complexes
( DNA and RNA: Properties and Modifications, Functions and Interactions, Recombination and Applications )
Publication series ：DNA and RNA: Properties and Modifications, Functions and Interactions, Recombination and Applications
Author： Nikolai Vekshin (Russian Academy of Sciences Moscow Russia)
Publisher： Nova Science Publishers, Inc.
Publication year： 2014
E-ISBN: 9781617615214
Subject： Q968 Insect Ecology and insect geography
Keyword： Biology
Language： ENG
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Description
This book presents the basic results on studies of the interaction of anti-cancer Actinomycin antibiotics with DNA. It focuses on interactions of heterocyclic anti-tumor antibiotics (Actinomycins, as typical example) with DNA, poly-nucleotides, oligonucleotides, and aggregates of purines, using spectroscopic methods. Experimental data, various models of structures of the complexes and their physical and chemical properties are described, and possible approaches for delivery of heterocyclic antibiotics to DNA are also discussed.