MicroRNA's in solid cancer: From biomarkers to theraputic MicroRNA's
( DNA and RNA: Properties and Modifications, Functions and Interactions, Recombination and Applications )
Publication series ：DNA and RNA: Properties and Modifications, Functions and Interactions, Recombination and Applications
Author： Ondrej Slaby (Masaryk Memorial Cancer Institute Czech Republic)
Publisher： Nova Science Publishers, Inc.
Publication year： 2012
E-ISBN: 9781624173639
Subject： Q522 ribose (deoxyribose nucleic acid (RNA)
Keyword： Cancer
Language： ENG
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Description
MiRNA is an extremely fast growing field, and miRNA knowledge is now believed to be a pivotal element of cancer biology. It is already evident that the discovery of miRNA has created a paradigm shift in post-genomics biology, not only for scientists accustomed to traditional central dogma of molecular biology but also for researchers studying human diseases and accustomed to traditional genetics approach of studying one gene at the time. This book provides an introduction to the basic principles of miRNA biology, overview of miRNA significance in the hallmarks of cancer, experimental techniques used in miRNA research, and in special part - miRNAs importance in wide range of solid cancers with a special focus on its potential usage in molecular pathology, predictive oncology or as a novel therapeutic targets.