Publication series :Pharmacology - Research, Safety Testing and Regulation
Author: Gerond V. Lake-Bakaar (Beth Israel Deaconess Medical Center Boston MA)
Publisher: Nova Science Publishers, Inc.
Publication year: 2012
E-ISBN: 9781622575473
Subject: R979.1 anti - tumor, anti - cancer drug
Keyword: Pharmacology
Language: ENG
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Description
Rituximab (MabThera(r), Rituxan(r)) is a chimaeric murine/human antibody targeted against the surface antigen CD20 that is expressed on normal and malignant human mature B cells, but not stem cells or plasma cells. It is potentially the proverbial magic bullet for diseases associated with B cell disorders as well as a probe for elucidating the role of B cells in health and disease. This book explores the full spectrum of activity of Rituximab in man.