Diet-Microbe Interactions in the Gut :Effects on Human Health and Disease

Publication subTitle :Effects on Human Health and Disease

Author: Tuohy   Kieran;Rio   Daniele Del  

Publisher: Elsevier Science‎

Publication year: 2014

E-ISBN: 9780124079410

P-ISBN(Paperback): 9780124078253

Subject: R3 Basic Medical;R9 Pharmacy;TS2 food industry

Keyword: 微生物学,普通生物学,临床医学,预防医学、卫生学,基础医学,内科学

Language: ENG

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Description

Drawing on expert opinions from the fields of nutrition, gut microbiology, mammalian physiology, and immunology, Diet-Microbe Interactions for Human Health investigates the evidence for a unified disease mechanism working through the gut and its resident microbiota, and linking many inflammation-related chronic diet associated diseases. State of the art post-genomic studies can highlight the important role played by our resident intestinal microbiota in determining human health and disease. Many chronic human diseases associated with modern lifestyles and diets — including those localized to the intestinal tract like inflammatory bowel disease and celiac disease, and more pervasive systemic conditions such as obesity, diabetes and cardiovascular disease — are characterized by aberrant profiles of gut bacteria or their metabolites. Many of these diseases have an inflammatory basis, often presenting with a chronic low-grade systemic inflammation, hinting at persistent and inappropriate activation of inflammatory pathways. Through the presentation and analysis of recent nutrition studies, this book discusses the possible mechanisms underpinning the disease processes associated with these pathologies, with high fat diets appearing to predispose to disease, and biologically active plant components, mainly fiber and polyphenols, appearing to reduce the risk of chronic disease development.

  • One comprehensive, translational source for all aspects of nutrition and

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