Publisher: Karger
E-ISSN: 1421-9794|44|6|377-384
ISSN: 0009-3157
Source: Chemotherapy, Vol.44, Iss.6, 1998-10, pp. : 377-384
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
β-Lactam resistance on the part of the Enterobacteriaceae causes serious therapeutic problems in our institutions due to their production of extended-spectrum β-lactamases (ESβLs). We studied the in vitro activity of β-lactam/β-lactamase inhibitor combinations and third-generation cephalosporins and monobactams against 71 clinically relevant Enterobacteriaceae which produced TEM- and SHV-derivative ESβLs. Of the single drugs and combinations tested, piperacillin/tazobactam proved to be the most effective. Piperacillin/tazobactam was highly active against
Related content
By Gay Noellie Leclaire Alexandre Laval Morgane Miltgen Guillaume Jégo Maël Stéphane Ramin Jaubert Julien Belmonte Olivier Cardinale Eric
Veterinary Sciences, Vol. 5, Iss. 1, 2018-02 ,pp. :