Applied Pharmacology

Author: Bardal   Stan  

Publisher: Elsevier Health Sciences‎

Publication year: 2010

E-ISBN: 9781437735789

Subject: C0 Social Science Theory and Methodology

Language: ENG

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Chapter

Website

Chapter 2: Pharmacokinetics

Basic Concepts

Absorption

Drug Distribution

Drug Elimination

Clinical Pharmacokinetics

Chapter 3: Autonomic Pharmacology

Autonomic Anatomy

Parasympathetic Drugs

Sympathetic Drugs

Chapter 4: Drug Interactions

Mechanisms of Drug Interactions

Characteristics of Drug Interactions

Assessing the Clinical Impact of Drug Interactions

Resources

Websites

Chapter 5: Impact of Age on Pharmacology

Fetus

Neonates, Infants, and Children

Lactation

Elderly

Summary and Clinical Context

Chapter 6: Pharmacogenetics

The Promise of Personalized Medicine

Pharmacogenetics and Pharmacogenomics

Pharmacokinetics

Pharmacodynamics

The Next Step: from Genetics to Genomics

Limitations of Pharmacogenomics

Resources for Pharmacogenetic Information

Chapter 7: Toxicology

General Principles

General Strategies for Management of Toxic Events

Pharmacologic Treatment of Specific Intoxications

Websites

Chapter 8: Herbal Medications

Regulatory Issues

Use of Herbal Medicines

Reliability of Herbal Products

Efficacy of Herbal Medications

Specific Herbal Medications

Websites

Chapter 9: Drug Discovery and Evaluation

Preclinical Process

Clinical Process

Chapter 10: Addiction and Abuse

Scope of the Substance Abuse Problem

Neurophysiology of Addiction

Opioids

Ethanol

Central Nervous System Stimulants

Cannabis

Hallucinogens

Inhalants

Section II: Drug Classes

Chapter 11: Cardiology

Angiotensin-Converting Enzyme Inhibitors (ACEIs)

Angiotensin Receptor Blockers (ARBs)

Direct Renin Inhibitors

Sodium Channel Blockers (Class I Antiarrhythmics)

β Antagonists (β-Blockers)

Potassium Channel Blockers (Class III Antiarrhythmics)

Calcium Channel Blockers

Anticholinergics

Adenosine

Digoxin

Inhibitors of Cholesterol Synthesis: Statins

Fibrates

Bile Acid Sequestrants

Inotropes and Pressors

Phosphodiesterase-3 Inhibitors

Nitrates

Vasodilators

Natriuretic Peptides

Chapter 12: Cough, Cold, and Allergy

Antitussives

Expectorants

Decongestants

H1 Antagonists

Mast Cell Stabilizers

Chapter 13: Dermatology

Retinoids

Steroids, Topical

Keratolytics

Imiquimod

Chapter 14: Endocrinology

a-Glucosidase Inhibitors (AGIs)

Biguanides

Incretins

Insulins

Meglitinides

Sulfonylureas

Thiazolidinediones

Glucagon

Estrogens

Estrogen Receptor Antagonists

Aromatase Inhibitors (AIs)

Progestins

Hormone Contraception

Oxytocin

Reproductive Prostaglandins (PGs)

Nonsteroidal Androgen Antagonists (NSAAs)

Androgens

Somatostatin Analogs

Growth Hormone Antagonists

Adrenocorticotropic Hormone (ACTH)

Thyroid Replacements

Antithyroids

Chapter 15: Gastroenterology

Antacids: Buffers

H2 Antagonists

Proton Pump Inhibitors (PPIs)

Chapter 16: Hematology

Heparins

Direct Factor Xa Inhibitors

Direct Thrombin Inhibitors

Vitamin K Antagonists

Salicylates

Adenosine Diphosphate (ADP) Blockers

Antiplatelet IIb/IIIa Inhibitors

Fibrinolytics

Erythropoietins

Colony-Stimulating Factors

B Vitamins

Iron

Chapter 17: Immune Modifiers

Systemic Steroids

Introduction to Monoclonal Antibodies

B-Cell Biologics

T-Cell Biologics

Mixed Biologics

Tumor Necrosis Factor (TNF)–α Inhibitors

Antimetabolites

Calcineurin Inhibitors

Target of Rapamycin (mTOR) Inhibitors

Activated Protein C

Glatiramoids

Chapter 18: Infectious Diseases

Introduction to Antibiotics

Penicillins

Cephalosporins

Carbapenems

Glycopeptides

Fluoroquinolones

Aminoglycosides

Lincosamides

Tetracyclines

Macrolides

Oxazolidinones

Sulfonamides and Other Folate Synthesis Inhibitors

Metronidazole

Introduction to Antimycobacterials

Ethambutol

Isoniazid

Pyrazinamide

Rifamycins

CCR5 Antagonists

Fusion Inhibitors

Integrase Inhibitors

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

Nonnucleoside Reverse Transcriptase Inhibitors (nNRTIs)

Protease Inhibitors

Uncoating Inhibitors

Neuraminidase Inhibitors

Nucleoside Analogues

Azoles

Echinocandins

Griseofulvin

Polyenes

Pyrimidine Antifungals

Terbinafine

Quinolines

Anthelmintics

Antiprotozoals

Chapter 19: Musculoskeletal System

Bisphosphonates (BPs)

Vitamin D Replacement

Parathyroid Hormone

RANKL Inhibitors

Colchicine

Nonsteroidal Antiinflammatory Drugs (NSAIDs)

Uricosurics

Xanthine Oxidase Inhibitors

Chapter 20: Neoplasia

Alkylators

Anthracyclines

Antimetabolites

Bleomycin

Platinum Compounds

Taxanes

Topoisomerase Inhibitors

Vinca Alkaloids

Gonadotropin-Releasing Hormone (GnRH) Analogues

Angiogenesis Inhibitors

Tyrosine Kinase Inhibitors

Chapter 21: Neurology and the Neuromuscular System

Acetaminophen

Opioids

α2 Agonists

Inhaled Anesthetics

Intravenous Anesthetics

Local Anesthetics

Baclofen

Nondepolarizing Neuromuscular Blockers

Depolarizing Neuromuscular Blockers

Nicotine

Dopamine and Dopamine Agonists

Catechol-O-Methyl Transferase (COMT) Inhibitors

Cholinesterase Inhibitors

Ergot Alkaloids

Triptans

Topiramate

Phenytoin

Lamotrigine

γ-Aminobutyric acid (GABA) Analogues

Carbamazepine

Barbiturates

Valproate

Chapter 22: Ophthalmology

Ophthalmic Prostaglandins

Aptamers

Chapter 23: Psychiatry

Selective Serotonin Reuptake Inhibitors (SSRIs)

Tricyclic Antidepressants (TCAs)

Serotonin Noradrenaline Reuptake Inhibitors (SNRIs)

Noradrenergic and Specific Serotonergic Antidepressants (NaSSAs)

Monoamine Oxidase Inhibitors (MAOIs)

Noradrenaline and Dopamine Reuptake Inhibitors (NDRIs)

Lithium

First-Generation Antipsychotics

Second-Generation Antipsychotics

Benzodiazepines

Central Nervous System Stimulants

Chapter 24: Pulmonary System

Beta 2 (β2) Agonists (Bronchodilators)

Inhaled Anticholinergics

Leukotriene Receptor Antagonists

Methylxanthines

Inhaled Corticosteroids

Phosphodiesterase-5 Inhibitors

Endothelin Receptor Antagonists

Vascular Prostaglandins

Chapter 25: Renal and Genitourinary Systems

Thiazide Diuretics

Loop Diuretics

Potassium-Sparing Diuretics

Carbonic Anhydrase Inhibitors (CAIs)

Osmotic Diuretics

Antidiuretic Hormone (Vasopressin) Analogues

Anticholinergics: Bladder

Alpha-1 (α1) Antagonists

5α-Reductase Inhibitors

Index

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