Chapter
Research on Model Organisms Helps Clarify Gene Function
WHICH TREATMENTS AND INTERVENTIONS WILL HELP?
Interventions Can Reduce ASD Symptoms Substantially
WHERE CAN I TURN FOR SERVICES?
Multistate Survey Confirms High Prevalence of ASD
WHAT DOES THE FUTURE HOLD?
Autism Costs U.S. Society More Than $35 Billion per Year
APPENDIX A - LIST OF CONTACTED FEDERAL AND PRIVATE ORGANIZATIONS THAT FUND ASD RESEARCH
Federal Agencies Contacted
Private Organizations Contacted
Chapter 2 SUMMARY OF ADVANCES IN AUTISM SPECTRUM DISORDER RESEARCH: CALENDAR YEAR 2008
OVERVIEW OF AUTISM FINDINGS IN 2008
Diagnosis: When Should I Be Concerned?
Biology: How Can I Understand What Is Happening?
Risk Factors: What Caused This to Happen and CanIt Be Prevented?
Treatment: Which Treatments and Interventions Will Help?
Services and Supports: Where Can I Turn for Services?
Outcomes: What Does the Future Hold?
Diagnosis: When Should I Be Concerned?
Biology: How Can I Understand What Is Happening?
Risk Factors: What Caused This to Happen and CanIt Be Prevented?
Treatment: Which Treatments and Interventions Will Help?
Services and Supports: Which Treatments and Interventions Will Help?
Outcomes: What Does the Future Hold?
ARTICLES SELECTED FOR 2008 SUMMARYOF ADVANCES
Chapter 3 2009 SUMMARY OF ADVANCES IN AUTISM SPECTRUM DISORDER RESEARCH
THE 2009 IACC SUMMARY OF ADVANCES IN AUTISM SPECTRUM DISORDER RESEARCH
Articles Selected for the 2009 Summary of Advances
Medication and Parent Training in Children with Pervasive Developmental Disorders and Serious Behavior Problems: Results from a Randomized Clinical Trial – Aman, et al. Journal of the American Academy of Child and Adolescent Psychiatry. December 2009
Association of Family History of Autoimmune Diseases and Autism Spectrum Disorders – Atladóttir, et al. Pediatrics. August 2009
Genome-Wide Analyses of Exonic Copy Number Variants in a Family-Based Study Point to Novel Autism Susceptibility Genes – Bucan, et al. Plos Genetics. June 2009
Prevalence of Autism Spectrum Disorders – Autism and Developmental Disabilities Monitoring Network, United States, 2006 – Centers for Disease Control and Prevention. Morbidity and Mortality Weekly Report (MMWR) Surveillance Summaries. December 2009
Autism Genome-Wide Copy Number Variation Reveals Ubiquitin and Neuronal Genes – Glessner, et al. Nature. May 2009
Genomic and Epigenomic Evidence for Oxytocin Receptor Deficiency in Autism – Gregory, et al. BMC Medicine. October 2009
Risk of Autism and Increasing Maternal and Paternal Age in a Large North American Population – Grether, et al. American Journal of Epidemiology. November 2009
Representation of Internal Models of Action in the Autistic Brain – Haswell, et al. Nature Neuroscience. August 2009
Incidence of Gastrointestinal Symptoms in Children with Autism: A Population-Based Study – Ibrahim, et al. Pediatrics. August 2009
Diagnostic Change and the Increased Prevalence of Autism – King and Bearman. International Journal of Epidemiology. October 2009
Two-Year Olds with Autism Orient to Non-Social Contingencies Rather Than Biological Motion – Klin, et al. Nature. May 2009
Prevalence of Parent-Reported Diagnosis of Autism Spectrum Disorder Among Children in the US, 2007 – Kogan, et al. Pediatrics. November 2009
Racial/Ethnic Disparities in the Identification of Children with Autism Spectrum Disorders – Mandell, et al. American Journal of Public Health. March 2009
Abnormal Behavior in a Chromosome-Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism – Nakatani, et al. Cell. June 2009
Autism and Other Neuropsychiatric Symptoms Are Prevalent in Individuals with MECP2 Duplication Syndrome – Ramocki, et al. Annals of Neurology. December 2009
Timing of Identification Among Children with an Autism Spectrum Disorder: Findings from a Population-Based Surveillance Study – Shattuck, et al. Journal of the American Academy of Child and Adolescent Psychiatry. May 2009
Partial Reversal of Rett Syndrome-Like Symptoms in MECP2 Mutant Mice – Tropea, et al. Proceedings of the National Academy of Sciences USA. February 2009
Common Genetic Variants on 5p14.1 Associate with Autism Spectrum Disorders – Wang, et al. Nature. May 2009
A Genome-Wide Linkage and Association Scan Reveals Novel Loci for Autism – Weiss, et al. Nature. October 2009
Clinical Assessment and Management of Toddlers with Suspected Autism Spectrum Disorder: Insights from Studies of High-Risk Infants – Zwaigenbaum, et al. Pediatrics. May 2009
Chapter 4 2010 SUMMARYOF ADVANCES IN AUTISM SPECTRUM DISORDER RESEARCH
THE 2010 IACC SUMMARYOF ADVANCES IN AUTISM SPECTRUMDISORDER RESEARCH
ARTICLES SELECTED FOR THE 2010 SUMMARYOF ADVANCES
Question 1: Diagnosis - When Should I Be Concerned?
Implementing Developmental Screening and Referrals: Lessons Learned from a National Project
Consensus Statement: Chromosomal Microarray Is a First-Tier Clinical Diagnostic Test for Individuals with Developmental Disabilities or Congenital Anomalies
Automated Vocal Analysis of Naturalistic Recordings from Children with Autism, Language Delay, and Typical Development
A Prospective Study of the Emergence of Early BehavioralSigns of Autism
Question 2: Biology - How Can I Understand What is Happening?
Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals with ASDs: A Consensus Report
Recommendations for Evaluation and Treatment of Common Gastrointestinal Problems in Children with ASDs
Describing the Brain in Autism in Five Dimensions – Magnetic Resonance Imaging-Assisted Diagnosis of Autism Spectrum Disorder Using a Multiparameter Classification Approach
Mitochondrial Dysfunction in Autism
Neural Signatures of Autism
A Model for Neural Development and Treatment for Rett Syndrome Using Human Induced Pluripotent Stem Cells
Longitudinal MRI Study of Cortical Development Through Early Childhood in Autism
Question 3: Risk Factors - What Caused This to Happen and Can It Be Prevented?
Mutations in the SHANK2 Synaptic Scaffolding Gene in Autism Spectrum Disorder and Mental Retardation
Blood Mercury Concentrations in CHARGE Study Children with and without Autism
Functional Impact of Global Rare Copy Number Variation in Autism Spectrum Disorder
Altered Functional Connectivity in Frontal Lobe Circuits Is Associated with Variation in the Autism Risk Gene CNTNAP2
Question 4: Interventions - Which Treatments and Interventions Will Help?
Randomized, Controlled Trial of an Intervention for Toddlers with Autism: The Early Start Denver Model
Randomized Controlled Caregiver Mediated Joint Engagement Intervention for Toddlers with Autism
Evaluation of Comprehensive Treatment Models for Individuals with Autism Spectrum Disorders
Evidence-Based Practices in Interventions for Children and Youth with Autism Spectrum Disorders
Question 5: Services - Where Can I Turn for Services?
Can State Early Intervention Programs Meet the Increased Demand of Children Suspected of Having Autism Spectrum Disorders?
Question 6: Lifespan - What Does the Future Hold, Particularly for Adults?
Question 7: Infrastructure - What Other Infrastructure and Surveillance Needs Must Be Met?
Changes in Autism Spectrum Disorder Prevalence in 4 Areas of the United States
FULL LISTING OF NOMINATED ARTICLES
Question 1: When Should I Be Concerned?
Question 2: How Can I Understand What Is Happening?
Question 3: What Caused This to Happen and CanIt Be Prevented?
Question 4: Which Treatments and Interventions Will Help?
Question 5: Where Can I Turn for Services?
Question 6: What Does the Future Hold, Particularlyfor Adults?
Question 7: What Other Infrastructure and Surveillance Needs Must Be Met?
Chapter 5 2011 SUMMARY OF ADVANCES IN AUTISM SPECTRUM DISORDER RESEARCH
ARTICLES SELECTED FOR THE 2011 SUMMARYOF ADVANCES
Question 1: When Should I Be Concerned
Disrupted Neural Synchronization in Toddlers with Autism
Detecting, Studying, And Treating Autism Early: The One-Year Well-Baby Check-Up Approach
Question 2: How Can I Understand What Is Happening?
Mutations Causing Syndromic Autism Define an Axisof Synaptic Pathophysiology
Absence of CNTNAP2 Leads to Epilepsy, Neuronal Migration Abnormalities, and Core Autism-Related Deficits
Protein Interactome Reveals Converging Molecular Pathways
Transcriptomic Analysis of Autistic Brain Reveals ConvergentMolecular Pathways
Question 3: What Caused This to Happen and CanIt Be Prevented?
Genetic Heritability and Shared Environmental Factors Among Twin Pairs with Autism
Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders
Exome Sequencing In Sporadic Autism Spectrum Disorders Identifies Severe De Novo Mutations
Recurrence Risk for Autism Spectrum Disorders: A Baby Siblings Research Consortium Study
Multiple Recurrent De Novo Cnvs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism
Question 4: Which Treatments and Interventions Will Help?
A Systematic Review of Medical Treatments for Children with Autism Spectrum Disorders
Intervention Targeting Development of Socially Synchronous Engagement in To
Randomized, Controlled Trial of The LEAP Model of Early Intervention for Young Children with Autism Spectrum Disorders
Question 5: Where Can I Turn for Services?
Post-High School Service Use Among Young Adults with an Autism Spectrum Disorder
Question 6: What Does the Future Hold, Particularlyfor Adults?
Epidemiology of Autism Spectrum Disorders in Adults in the Community In England
Autism Spectrum Disorders in Older Adults: Toward Defininga Research Agenda
Emerging New Practices in Technology to Support Independent Community Access for People with Intellectual and Cognitive Disabilities
Question 7: What Other Infrastructure and Surveillance Needs Must Be Met?
Trends in The Prevalence of Developmental Disabilities in US Children 1997-2008
Prevalence of Autism Spectrum Disorders in a Total Population Sample
FULL LISTINGOF NOMINATED ARTICLES
Question 1: When Should I Be Concerned?
Question 2: How Can I UnderstandWhat Is Happening?
Question 3: What Caused This to Happenand Can It Be Prevented?
Question 4: Which Treatments and InterventionsWill Help?
Question 5: Where Can I Turn for Services?
Question 6: What Does the Future Hold, Particularlyfor Adults?
Question 7: What Other Infrastructure and Surveillance Needs Must Be Met?
Advances in Autism Spectrum Disorder Research: Summaries, 2007-2011
( Neurodevelopmental Diseases - Laboratory and Clinical Research )
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