Molecular Mechanisms for Sensory Signals :Recognition and Transformation ( Princeton Legacy Library )

Publication subTitle :Recognition and Transformation

Publication series :Princeton Legacy Library

Author: Kosower Edward M.  

Publisher: Princeton University Press‎

Publication year: 2017

E-ISBN: 9781400887088

P-ISBN(Paperback): 9780691085531

Subject: Q42 nerve physiology

Keyword: 生物化学

Language: ENG

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Description

Pursuing the questions of how we learn and how memory is made, Edward Kosower introduces a novel and rich approach to connecting molecular properties with the biological properties that enable us to write and read, to create culture and ethics, and to think. Here he examines what happens within a single cell in reaction to external stimuli, and shows the parallels between single cell and multicellular responses. To address the problem of "learning," Kosower explains the molecular mechanisms of responses to input from taste, olfactory, and visual receptors. He then shows how these and other processes serve as the basis for memory. This study covers such signals for the molecular process of learning as pheromones (the molecular signals mediating behavior), light (activates the G-protein receptor, rhodopsin), and acetylcholine (opens the nicotinic acetylcholine receptor). Kosower's discussion of the structure and function of these complex molecules has direct implications for such areas as molecular neurobiology, bioorganic chemistry, and drug design, in elucidating approaches to the structure of drug targets.

Originally published in 1991.

The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The g

Chapter

List of Illustrations

List of Tables

Preface

1. Hierarchies in Natural Systems

2. Chemotaxis

3. Sensory Transduction: Pheromones and Taste

4. Olfactory System

5. Visual System

6. The Nicotinic Acetylcholine Receptor

7. Molecular Models for Sodium Channels

8. Receptor and Channel Superfamilies

9. Learning and Memory

References

Author Index

Subject Index

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