The Role of Global Air Pollution in Aging and Disease ：Reading Smoke Signals

Publication subTitle ：Reading Smoke Signals

Author： Finch   Caleb E.  

Publisher： Elsevier Science‎

Publication year： 2018

E-ISBN: 9780128131039

P-ISBN(Paperback): 9780128131022

Subject： R122.2 Air hygiene

Keyword： 老年病学,医药、卫生

Language： ENG

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Description

Global Air Pollution in Aging: Reading Smoke Signals is a complete reference connecting environmental pollution research to the human aging process. Since 1800, lifespans have more than doubled as infections declined and medicine improved. But the 20th century introduced a new global scourge of air pollution from fossil fuels with the potential to damage arteries, hearts and lungs that has been related to chronic exposure of air pollution from fossil fuels. Risk areas of study include childhood obesity, brain damage associated with air pollution, increased risk for autism in children and dementia in older adults.

In humans and animals, air pollution stimulates chronic inflammation in different organs, and genetic vulnerability to air pollution is being recognized, particularly for carriers of the Alzheimer risk gene ApoE4.

  • Connects environmental pollution research to the human aging process
  • Raises new issues relevant to the controversies on air pollution and global warming, challenging assumptions that lifespan will continue to increase in the 21st Century
  • Examines the burden of air pollution to disadvantaged populations, with anticipated greater impact in developing countries which rely on fossil fuels for economic development in future decades

Chapter

Front Cover

The Role of Global Air Pollution in Aging and Disease

The Role of Global Air Pollution in Aging and Disease

Copyright

Dedication

Contents

Preface

REFERENCES

Acknowledgments

1 - The Three Smokes in Global Mortality

1.1 OVERVIEW

1.2 AIRBORNE TOXINS, A PRIMER

1.3 CAVEATS FROM CIGARETTES

1.4 THE THREE SMOKES AND MORTALITY

1.4.1 Ambient Air Pollution

1.4.2 Cigarettes

1.4.3 Biomass Smoke, Inside and Out

1.4.4 Plus Dust

1.5 INTERACTIONS OF THE THREE SMOKES

1.6 THE HISTORY OF AIR POLLUTION DURING EXPANDING LONGEVITY

1.7 CONCLUSIONS

REFERENCES

2 - The Toxic Nature of the Three Smokes

2.1 OVERVIEW

2.2 PARTICLE SIZE AND CHEMISTRY

2.3 SOURCE APPORTIONMENT IN MORBIDITY AND MORTALITY

2.4 CIGARETTE SMOKE

2.5 HOUSEHOLD AIR POLLUTION, BIOMASS SMOKE, AND DUST

2.6 MECHANISMS

2.6.1 Blood Cells and Lung Epithelial Cells

2.6.2 Brain Cell Responses

2.7 THE DARK PASSAGE: DOES INHALED PARTICULATE MATTER REACH THE BRAINS OF ADULTS AND EMBRYOS?

2.8 CONCLUSIONS

REFERENCES

3 - Air Pollution in Diseases of Aging

3.1 OVERVIEW

3.2 ARTERIAL THICKENING AND ATHEROMA FORMATION

3.2.1 Cigarette Smoke

3.2.2 Ambient Air Pollution

3.2.3 Biomass Smoke

3.3 THE BRAIN

3.3.1 Cigarette Smoke

3.3.2 Ambient Air Pollution

3.3.3 Biomass Smoke

3.4 INTERACTIONS OF AMBIENT AIR POLLUTION AND CIGARETTE SMOKE

3.5 CONCLUSIONS

REFERENCES

4 - Air Pollution and Cigarettes Cloud Development

4.1 OVERVIEW

4.2 PREMATURITY, BIRTHWEIGHT, AND PLACENTATION

4.3 BODY WEIGHT AND OBESITY

4.4 BRAIN DEVELOPMENT

4.5 MECHANISMS

4.6 EPIGENETICS

4.7 CONCLUSIONS

REFERENCES

5 - Air Pollution in Our Future Longevity

5.1 OVERVIEW

5.2 TRENDS IN AIR POLLUTION

5.2.1 Persistence of the Three Smokes Beyond 2020

5.2.2 Tobacco

5.2.3 Global Warming and Air Pollution

5.2.4 Mosquito Days

5.3 HEALTH BENEFITS FROM REDUCING EXPOSURE TO AIR POLLUTANTS

5.3.1 Mortality

5.3.2 Lung Function

5.3.3 Cigarette Smoking

5.4 TRENDS IN LONGEVITY: DOES OUR EVOLUTIONARY PAST PREDICT THE FUTURE?

5.5 WHEN THE FUTURE EXPOSOME MEETS THE GENOME OF THE PAST

5.6 READING SMOKE SIGNALS: A SYNOPSIS

5.7 CONCLUSION

REFERENCES

Glossary

Subject Index

Brain Structures by name

Chemicals by name

Countries and Geographic Regions by name

Genes by name

Researchers by name

Studies by name

Universities by name

Stand alone

Back Cover

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