Chapter
On the Nature of Obsessions and Compulsions
Open Questions and Suggestions for Answers
The Origin of Anxiety Disorders – An Evolutionary Approach
The Brain: Evolution and Complexity
Neurocircuitry of Anxiety Disorders
Posttraumatic Stress Disorder
Generalized Anxiety Disorder
Obsessive-Compulsive Disorder
The Importance of Distance from a Threat
Genetic Factors in Anxiety Disorders
Molecular Genetic Studies
Serotonin/Norepinephrine System Genes
Cholecystokinin System Genes
Hypothalamus-Pituitary-Adrenal Axis-Related Genes
Gene-Gene Interaction Studies
Genome-Wide Association Studies
Gene-Environment Interaction Studies
Genetic Studies in Intermediate Phenotypes
Peripheral Sympathetic Activity
Carbon Dioxide Reactivity
Cholecystokinin Challenge
Neural Correlates of Emotional Processing
Pharmacogenetic and Psychotherapy-Genetic Studies
Neuroimaging in Anxiety Disorders
Meta-Analysis of Anxiety Neuroimaging
Symptom Provocation and Fear Network Activity
Multiple Mechanisms Mediating Anxiety
Potential Neuroimmunological Targets in the Treatment of Anxiety Disorders
The Pivotal Role of Cytokines
The Neuroimmunology of Depression
Immunomodulating Effects of Antidepressants
A Neuroimmunology of Anxiety Disorders?
Inflammatory Responses and the Anxious State
Inflammatory Responses in Anxiety Disorders
Post-Traumatic Stress Disorder
Obsessive-Compulsive Disorder
Generalized Anxiety Disorder
The Limitations of Current Knowledge
Recommendations for Future Research
Longitudinal Study Design
Standardized Measures of Inflammatory Biomarkers
Standardized Behavioural Assessments and Record of Inflammatory Events
Development of Novel Measurement Strategies
Genetic Polymorphism of Cytokines
Clinical and Pharmacotherapeutic Implications
Anxiety and Cardiovascular Disease
Association of Anxiety Disorders with Hypertension
Mechanisms in the Association of Hypertension and Panic Attacks/Panic Disorder
Other Putative Mechanisms
Anxiety and Coronary Heart Disease
Mechanisms in the Association of Coronary Heart Disease and Anxiety
The Early Phases of Anxiety Disorders: From Prevention to Treatment
Application of the Early Intervention Model to Anxiety Disorders
New Concepts for Health Prevention
Predictors of Anxiety Disorders
Duration of Untreated Illness in Anxiety Disorders
The Early Stages of Anxiety Disorders
The ‘at Risk Asymptomatic’
Incomplete Recovery, Relapse and Treatment Resistance after the First Episode
Objectives of Early Intervention in Anxiety Disorders
Prevention and Intervention in the Early Stages of Anxiety Disorders
Service Repercussions of Applying the Early Intervention Model to Anxiety and Obsessive Compulsive Disorders
Duration of Untreated Illness and Duration of Illness in Anxiety Disorders: Assessment and Influence on Outcome
Anxiety Disorders, Duration of Untreated Illness and Duration of Illness
Duration of Untreated Illness
Duration of Untreated Illness, Epidemiology and Clinical Outcome in Anxiety Disorders
Pharmacotherapy of Generalized Anxiety Disorder
Prevalence of Generalized Anxiety Disorder in Population Samples and in Primary Care
Insomnia in Generalized Anxiety Disorder
Evidence-Based Generalized Anxiety Disorder Treatments
Pharmacological Treatment of Panic Disorder
Selective Serotonin Reuptake Inhibitors
Serotonin-Noradrenaline Reuptake Inhibitors
Tricyclic Antidepressants
Monoamine Oxidase Inhibitors
Comparisons between Drugs in the Treatment of Panic Disorder
Practical Guidelines for Treatment
Particular Patient Populations
Management of Treatment-Resistant Panic Disorder
Pharmacological Treatment of Social Anxiety Disorder
Recognition and Diagnosis
Social Anxiety and Psychosis
Presumed Neuropsychobiology
Further Management after Non-Response to Initial Treatment
Treatment of Social Anxiety Symptoms in Psychosis
Potential Novel Pharmacological Treatments
Pharmacotherapy of Posttraumatic Stress Disorder
Psychobiology of Posttraumatic Stress Disorder
Overview of the Pharmacotherapy of Posttraumatic Stress Disorder
Rationale for Pharmacotherapy
Evidence Base for Pharmacotherapy of Posttraumatic Stress Disorder
Determinants of Study Outcomes in Posttraumatic Stress Disorder
Brief Review of the Evidence of Pharmacotherapy in Posttraumatic Stress Disorder
Tricyclic Antidepressants
Monoamine Oxidase Inhibitors
Selective Serotonin Reuptake Inhibitors
Venlafaxine Extended Release
Evidence-Based Treatment Pathways for Translational Studies in Obsessive-Compulsive Disorders
Endophenotypes in Obsessive-Compulsive Disorder
Tools and Techniques for Measuring Clinical Response
Criteria for Response, Remission, Relapse and Resistance
Evidence-Based Treatments for Obsessive-Compulsive Disorder: Current Knowledge and Practice
Cognitive Behaviour Therapy or Serotonin Reuptake Inhibitor?
Monotherapy or Combination Treatment?
High-Dose SSRI or Adjunctive Antipsychotic in SSRI-Resistant Cases?
In-Patient Intensive Cognitive Behaviour Therapy or Somatic Therapies?
Determining a Research-Focussed Treatment Algorithm
Calculating the Sample Size for Treatment Cells
Anxiety Disorders
( Modern Trends in Pharmacopsychiatry )
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
