Description
Research into perspiration has developed dramatically during the last 15 years, continually improving our understanding of the pathogenesis of sweating disorders. It has become clear that, in addition to its temperature-regulating function, perspiration offers bactericidal protection as well. In this book, select authors further broaden our perspective on perspiration. Contributions cover a variety of new aspects, offering insight into the sweat glands' major role during the onset of disorders such as parapsoriasis, lichen planus, and lichen amyloidosis. They also highlight the importance of Malassezia - an allergen in sweat that exacerbates atopic dermatitis and cholinergic urticarial. Further roles of the sweat glands are discussed, including as storage of stem cells for replenishing epidermal cells in the case of thermal burns or as water retention sites for replenishing moisture in the stratum corneum. In addition, a novel analysis of the sweat glands' three-dimensional structures, using high-speed en-face optical coherence tomography (OCT), is introduced. Offering an in-depth overview of the latest knowledge in perspiration research, this book serves as an essential reference for all medical staff and researchers in the field.
Chapter
New Pathologies of Skin Disorders Identified from the History of Perspiration Research
Early Stage of Perspiration Research
Maturation Stage of Perspiration Research
Development Stage of Perspiration Research
Classification of Systemic and Localized Sweating Disorders
New Findings on the Mechanism of Perspiration Including Aquaporin-5 Water Channel
Immunohistochemical Analysis of Aquaporin-5 Localization in Human Eccrine Sweat Glands
Aquaporin-5 Translocates from the Nonapical Region to the Apical Membranes in Cells of Mouse Sweat Glands under Sweating Conditions
Transfected Human Aquaporin-5 Is Located at Both the Apical and Basolateral Membranes of Madin-Darby Canine Kidney Cells
Human Aquaporin-5 Translocates from the Cytoplasm to the Apical Membranes by Treatment with Calcium Ionophore
Anoctamin-1 Is Detected in the Apical Membranes and Colocalizes with Aquaporin-5
Aquaporin-5 in Sweat Glands
Old and New Approaches for Assessing Sweating
Other Methods for Obtaining Replicas of Sweat Drops and Sweat Pores
Measurement of Sweat Volume
Sympathetic Skin Response
Dynamic Imaging of Sweat and Sweat Glands
Sweat as an Efficient Natural Moisturizer
Physiological Functions of Sweat
Sweat Gland-/Duct-Related Skin Disease
Management of Sweat Gland-/Duct-Related Diseases
Genetic Disorders with Dyshidrosis: Ectodermal Dysplasia, Incontinentia Pigmenti, Fabry Disease, and Congenital Insensitivity to Pain with Anhidrosis
Congenital Insensitivity to Pain withAnhidrosis
Histamine Modulates Sweating and Affects Clinical Manifestations of Atopic Dermatitis
Sweating and Skin Barrier Function in Atopic Dermatitis
Sweating Affects Manifestations of Atopic Dermatitis
Histamine as a Factor to Reduce Sweating Ability
Managing Sweat in Patients with Atopic Dermatitis
Sweating in Systemic Abnormalities: Uremia and Diabetes Mellitus
Diabetes Mellitus and Sweating
Abberant Sudomotor Functions in Sjögren’s Syndrome: Comparable Study with Atopic Dermatitis on Dry Skin Manifestation
Diagnosis of Sjögren’s Syndrome
Pathomechanisms of Sjögren’s Syndrome
Cutaneous Manifestations of Sjögren’s Syndrome
Clinical Analysis and Management of Acquired Idiopathic Generalized Anhidrosis
Clinical Manifestations and Diagnosis
Dyshidrotic Eczema and Its Relationship to Metal Allergy
Relationship to Metal Allergy
Testing for Metal Allergy
Relationship to Sweat Ducts
Pathophysiology and Treatment of Hyperhidrosis
Concept and Pathology of Primary Focal Hyperhidrosis
Classification of Hyperhidrosis
Treatment and Treatment Algorithms
New Etiology of Cholinergic Urticaria
Clinical Tests for Cholinergic Urticaria
Sweat Allergy Type of Cholinergic Urticaria: Indirect Interaction of Acetylcholine with Mast Cells
Depressed Sweating Type of Cholinergic Urticaria: Direct Interaction of Acetylcholine with Mast Cells
Inflammatory Cell Infiltration around Eccrine Sweat Glands in Cholinergic Urticaria
Background of Sweat Allergy
Identification of MGL_1304 as a SweatAntigen
Establishment of an ELISA System MeasuringMGL_1304-Specific Immunoglobulins
Generation of Recombinant MGL_1304 by Pichia pastoris
How to Deal with Sweat Allergy
Perspiration Functions in Different Ethnic, Age, and Sex Populations: Modification of Sudomotor Function
Regional Differences of Sweating Activities
Sweating Responses Due to Acclimation
Individual and Racial Physical Factors Affecting Thermoregulation
Perspiration Research
( Current Problems in Dermatology )
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