Description
Since the publication of the first edition of 'Macular Edema - A Practical Approach' in 2010, modern imaging related to the pathophysiology of macular edema has progressed immensely. In particular, optical coherence tomography (OCT) techniques and new approaches, including "en face" OCT and OCT angiography, have become essential methods. This second, revised and extended edition incorporates the latest developments. It includes discussions of OCT-A imaging for better differential diagnosis and for state-of-the-art imaging figures. It elaborates practice guidelines and treatment algorithms, and also explores the pathophysiological basis of macular edema in detail. It discusses novel and various applications of drug delivery to the posterior segment. The latest peer-reviewed clinical studies are deliberated and real-world data from clinical settings offer additional new insights. This volume is a practical and useful update for all retina specialists interested in keeping abreast with the rapidly changing developments in the diagnosis and treatment of macular edema.
Chapter
Chapter 1: Macular Edema: Definition and Basic Concepts
Clinical Evaluation of Macular Edema
Chapter 2:
Mechanisms of Retinal Fluid Accumulation and Blood-Retinal Barrier Breakdown
Understanding Retinal Edema Based on Starling’s Law for Capillary Filtration
Breakdown of the Blood-Retinal Barrier and Macular Edema
Anatomic Considerations and Protein Movement
Role of Proteins and Osmotic Pressure in Driving Retinal Edema
Clinical Evaluation of the Blood-Retinal Barrier
Chapter 3: Intracellular Edema
Pathogenesis of Cystoid Macular Edema
Chapter 4: Central Serous Chorioretinopathy
Definition and Epidemiology
Diagnosis: Multimodal Imaging of Central Serous Chorioretinopathy
Central Serous Chorioretinopathy-Related Entities and Differential Diagnosis
Chapter 5: Diagnosis and Detection
Considering Macular Edema Based on the Disease
Chapter 6:
Optical Coherence Tomography Angiography in Macular Edema
Optical Coherence Tomography Angiography of Exudative Macular Edema
OCT Angiography of Ischemic Macular Edema ‘Cotton-Wool’ Spots
Chapter 7:
Macular Edema – Rationale for Therapy
Rationale for Medical Management
Rationale for Surgical Management of Macular Edema by Vitrectomy
Chapter 8: Drug Delivery to the Posterior Segment of the Eye
The Posterior Segment of the Eye and the Blood-Ocular Barrier
Strategies for Delivering Drugs to the Posterior Segment
Iontophoresis for Drug Delivery
Periocular/Sub-Tenon/Juxtascleral Drug Delivery
Drug Delivery to the Suprachoroidal Space
Chapter 9:
Diabetic Macular Edema
Definition and Classification
Chapter 10:
Retinal Vein Occlusions
Diagnosis: Imaging and Functional Testing, Stages, and Classifications
Chapter 11:
Insights into the Physiopathology of Inflammatory Macular Edema
Cellular Components of the Retinal Immune Response and Their Regulation
Mechanistic Pathways of Inflammatory Macular Edema
Chapter 12:
Postsurgical Cystoid Macular Edema
Definition and Epidemiology
Pathology and Pathophysiology
Staging and Classification
Best Sequential Management
Chapter 13:
Retinitis Pigmentosa and Other Dystrophies
Factors of Visual Acuity Decrease and Retinitis Pigmentosa
Retinitis Pigmentosa and Macular Edema
Melanoma and Cancer-Associated
Retinopathy
Chapter 14:
Macular Edema of Choroidal Origin
Pathophysiology: Theories of Macular Edema in Age-Related Macular Degeneration
Direct and Indirect Vascular Endothelial Growth
Chapter 15:
Miscellaneous
Macular Edema Resulting from Systemic or Topical Treatment
Epiretinal Membrane and Traction Syndrome
Tractional Myopic Vitreoschisis
Idiopathic Juxtafoveolar Retinal Telangiectasia
Macular Edema
：2nd, revised and extended edition
( Developments in Ophthalmology )
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