Description
The first edition of this volume, published in 2012, has become an indispensable reference for clinicians, a fact that inspired the making of this 2nd edition. The book starts with a discussion of current achievements and limitations of the medical therapy of glaucoma. The focus is then placed on conventional glaucoma procedures such as trabeculectomy, deep sclerectomy, and glaucoma drainage device surgery. A chapter is dedicated to the postoperative management of filtering procedures. Further chapters review the role of the ocular surface and the issue of modulation of the scarring processes in glaucoma surgery. The second section covers some promising new devices and techniques. The final part addresses the surgical approaches to some specific clinical challenges: angle-closure glaucoma, concomitant cataract and glaucoma, pediatric glaucoma, and refractory glaucomas. This volume provides residents and general ophthalmologists with valuable new insights into the fascinating and sometimes complex aspects of glaucoma surgery. It will also assist glaucoma specialists when they review and validate therapeutic approaches with their patients.
Chapter
Achievements and Limits of Current Medical Therapy of Glaucoma
Fixed Combination Antiglaucoma Therapies
Choosing a Medical Therapy
Adherence and Persistence
When to Perform Glaucoma Surgery
Enhanced Trabeculectomy: The Moorfields Safer Surgery System
Prevention of Complications
Glaucoma Drainage Implant Surgery
Glaucoma Drainage Implant Types
Comparison of Glaucoma Drainage Implant Types
The Role of Antifibrotics
Postoperative Management of Penetrating and Nonpenetrating External Filtering Procedures
Key Factors Promoting and Opposing Filtration
Preventing Complications: The Standard Postoperative Therapy
Recognizing Complications: Key Clinical Variables
Early Complications (Days to Weeks after Surgery)
Mid-Term Complications (Weeks to Months after Surgery)
Late Complications (Months to Years after Surgery)
Ocular Surface and External Filtration Surgery: Mutual Relationships
The Ocular Surface of Glaucomatous Patients
Histopathological Changes of the Conjunctiva in Glaucoma
Impression Cytology Specimens in Glaucoma
Clinical Evidence of Preservative-Induced Conjunctival Impairment
Possible Impact of Benzalkonium Chloride in Deep Ocular Structures
Increased Rate of Glaucoma Surgery Failure
Preoperative Assessment of Failure Risk
Postoperative Changes in the Ocular Surface
Postoperative Evaluation of the Bleb
Wound Healing and Glaucoma Surgery: Modulating the Scarring Process with Conventional Antimetabolites and New Molecules
Wound Healing in Glaucoma Filtration Surgery
Risk Factors for Failure of Glaucoma Filtration Surgery
Mechanism of Action of Mitomycin C
Technical Aspects of Mitomycin C Administration in Trabeculectomy: Site and Duration of Administration, Concentration and Sustained Delivery
Clinical Results with MMC-Augmented Trabeculectomy
Use of MMC in Tube Surgery and Nonpenetration Glaucoma Filtration Surgery
Mechanism of Action and Administration of 5-Fluorouracil
Clinical Results with 5-Fluorouracil-Augmented Trabeculectomy
Complications of Glaucoma Filtration Surgery Augmented with Antimetabolite Use
Needling Revision of Failing Filtration Blebs with Mitomycin C or 5-Fluorouracil Injections
New Molecules for Decreasing Postoperative Scar Formation, and Future Directions of Wound Healing Modulation in Glaucoma Filtration Surgery
Mini Drainage Devices for Anterior and Intermediate Filtration
The Safe Ex-PRESS Procedure
Laser-Assisted Techniques for Penetrating and Nonpenetrating Glaucoma Surgery
Laser-Assisted Techniques for Penetrating Filtering Surgery
Laser Use for Nonpenetrating FiltrationSurgery
Viscocanalostomy and Canaloplasty: ab Externo Schlemm’s Canal Surgery
Evaluation of the Aqueous Outflow System
Conclusions and Future Prospects
Ab interno Schlemm’s Canal Surgery
Description of Devices and Procedures
Surgical Treatment of Angle-Closure Glaucoma
Combined Cataract Extraction and Trabeculectomy
Glaucoma Drainage Implant
Minimally Invasive Glaucoma Surgery
Management of Concomitant Cataract and Glaucoma
Cataract Extraction Alone
Simultaneous or Sequential Cataract and Glaucoma Surgery
New Combined Interventions
Surgical Management of Pediatric Glaucoma
Cyclodestructive Procedures
When Should We Give Up Filtration Surgery: Indications, Techniques and Results of Cyclodestruction
Indications for Transscleral Cyclophotocoagulation and Endoscopic Cyclophotocoagulation
Methods for Transscleral Cyclophotocoagulation and Endoscopic Cyclophotocoagulation
Automated Ultrasound Cilioplasty: High-Intensity Focused Ultrasound