Pediatric Epidemiology ( Pediatric and Adolescent Medicine )

Publication series : Pediatric and Adolescent Medicine

Author: Kiess W.; Bornehag C.-G.; Gennings C.  

Publisher: S. Karger AG‎

Publication year: 2017

E-ISBN: 9783318061239

P-ISBN(Paperback): 9783318061222

Subject: R72 Pediatrics

Keyword: 医学遗传学,儿科学,预防医学、卫生学,传染病,流行病学与防疫

Language: ENG

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Description

Pediatric epidemiology differs substantially from general epidemiology especially when it comes to ethical, developmental and societal aspects. This unique book addresses biological considerations and ethical and legal questions in dealing with pediatric and adolescent populations. Classic topics, such as how to recruit representative samples, how to deal with confounding variables, and how to work with genetic information are the core areas of the book are also in focus. Last but not the least, this volume adds to the current understanding of global trends in occurrence, transmission, and control of epidemic pediatric diseases. This book not only serves as a textbook for epidemiologists, pediatricians, geneticists, and child and public health specialists but is also a key reference for those embarking on pediatric cohort studies and epidemiological studies involving the pediatric population.

Chapter

Ethical Issues in Paediatric Epidemiology

Abstract

Ethical Questions of Epidemiological Research on Children

The Vulnerability of Children as Probands

Between Health Research and Health Care – Theoretical Basis

(Institutionalised) Children in the View of Science. A Historical Retrospective of a Vulnerable Group of Probands

Good Epidemiological Practice – Ethical Guidelines for Epidemiological Research

References

Epidemiological Studies of Child Maltreatment: Difficulties and Possibilities

Abstract

Introduction

Definitions and Definition Problems

Research Sources

Population-Based Surveys

Specific Topics

Conclusions

References

Legislation on Genetic Testing in Different Countries

Abstract

Introduction

The European Union

Germany

Switzerland

France

The Netherlands

The United Kingdom

Portugal

The United States of America

Conclusions

Acknowledgement

References

The Dilemma Associated with Incidental Findings

Abstract

Incidental Findings and their Influence on Cohort Studies

The Usefulness versus the Risks of Incidental Findings for Participants

Frequency and Medical Relevance of Incidental Findings

Possible Strategy for Dealing with Incidental Findings in Cohort Studies

References

Challenges and Opportunities in Conducting Research in Developing Countries

Abstract

Background

Relevance of Research to Maternal and Child Health in Developing Countries

Prioritizing Research Areas and Topics

Translating Evidence into User-Friendly Communication Product

Conclusions and Recommendations

References

How to Recruit a Representative Sample and How to Look for It?

Abstract

Introduction

Ways to Achieve a Representative Gross Sample

Measures to Achieve Representative Response

Assessment of and Adjustment for Representativeness

References

The Epidemiology of Global Child Health

Abstract

The Child Survival Revolution

Determinants of Child Health and Survival

Equity in Global Child Health

The Need for Data

Future Challenges

References

How to Deal with Proxy-Reports

Abstract

Definitions

Proxy Perspectives

Proxy Selection

Quality of the Proxy-Report

Proxy-Reports and Missing Data

Proxy-Reports and Information Bias

Proxy Reports and Confounding

Self-Reports

Conclusions

References

Biology at a Young Age Differs from Biology at Later Ages: Developmental Aspects of Growth and Body Functions in Children and Young Adults

Abstract

Introduction

Age Determination in Children

Chronological Age Periods in Children

Gross Anatomy: Organ and Tissue Growth in Children

Body Size Measures

Longitudinal Growth Patterns

Pubertal Development

Age-Related Biochemical and Physiological Normative Reference Ranges in Children

References

Basic Epidemiology, Statistics, and Epidemiology Tools and Methods

Abstract

Hypotheses

Study Design

Data Sources

Statistical Analyses

Graphics

Hypothesis Testing and p Values

Statistical Software

Data Protection

The Concept of Standardization – What SDS Values Are For

References

How to Deal with Confounding

Abstract

Measures of Effect versus Measures of Association

Terminology

Criteria for a Confounder

Visualization of Confounding Using a DAG

Actions Against Confounding during Data Analysis

Examples of Confounding in Pediatric Epidemiology

Conclusion

References

Author Index

Subject Index

Cover

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