Cell Migration: Signalling and Mechanisms ( Translational Research in Biomedicine )

Publication series : Translational Research in Biomedicine

Author: Entschladen F.; Zänker K.S.  

Publisher: S. Karger AG‎

Publication year: 2009

E-ISBN: 9783805593229

P-ISBN(Paperback): 9783805593212

Subject: Q25 Cell Physiol.

Keyword: 分子生物学,细胞生物学,肿瘤学,医学免疫学

Language: ENG

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Description

Cell migration is a highly complex process which involves several compartments of the cell, including surface receptors, signalling elements and the cytoskeleton. It plays an essential role in embryogenesis, wound healing and inflammatory responses, and a dysregulation of cell movement can cause pathological states such as developmental defects, chronic inflammation, cancer invasion and metastasis.

Chapter

The Migrating Cell

Stem Cell Migration in Health and Disease

Leukocyte Motility and Human Disease

Coordination of Leukocyte Polarity and Migration

Positioning Phosphoinositide 3-Kinase in Chemokine and Antigen-Dependent T-Lymphocyte Navigation Mechanisms

Migration of Functionally Specialized T-Helper Cells: TFH Cells, Th17 Cells and FoxP3+ T Cells

ADAMs and Ectodomain Proteolytic Shedding in Leukocyte and Tumour Cell Migration

Guided Tour of Cell Migration: Signals and Pathways

Regulation of the E-Cadherin Adhesion Complex in Tumor Cell Migration and Invasion

The Cytoskeletal Connection: Understanding Adaptor Proteins

Locomotor Force Generation by Myosins

Author Index

Subject Index

Back cover

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