Controversies in the Treatment of Lung Cancer ( Frontiers of Radiation Therapy and Oncology )

Publication series : Frontiers of Radiation Therapy and Oncology

Author: Heide J.; Schmittel A.; Kaiser D.  

Publisher: S. Karger AG‎

Publication year: 2009

E-ISBN: 9783805592994

P-ISBN(Paperback): 9783805592987

Subject: R453 Drug therapy, chemical therapy;R56 Respiratory and thoracic diseases;R73 Oncology;R81 radiology

Keyword: 放射医学,呼吸系及胸部疾病,肿瘤学,药物疗法、化学疗法

Language: ENG

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Description

Under the auspices of the 12th International Symposium on Special Aspects in Radiotherapy 2008 in Berlin, acknowledged experts presented their perspectives on small and non-small cell lung cancer, reflecting the latest standards and engaging in controversies in the diagnosis and treatment of this disease.

Chapter

Histological Subtype: A Prognostic Factor in NSCLC

Squamous Cell Carcinoma Histological Subtypes Associated with Poor Prognosis

Adenocarcinoma Histological Subtypes Associated with Poor Prognosis

Bronchioloalveolar Cell Carcinoma Growth Pattern: A Favorable Prognostic Factor

Large Cell Carcinomas

Prognostic Implication of Molecular Markers

Conclusion

References

FDG-PET/CT in Lung Cancer: An Update

Abstract

Non-Small Cell Lung Cancer

Staging of Lung Cancer – Distant Metastases

Prediction and Monitoring Response to Therapy

Pleural Metastases

Cost-Effectiveness

Small Cell Lung Cancer

References

Whole-Body Magnetic Resonance Imaging for Staging of Lung Cancer

Abstract

Technical Aspects of Whole-Body MRI

Staging of Lung Cancer Using Whole-Body MRI

Conclusions

References

Bronchoscopy/Endobronchial Ultrasound

Abstract

EBUS-TBNA: Technique

Clinical Results

Complications

Conclusion

References

New Developments in Videomediastinoscopy: Video-Assisted Mediastinoscopic Lymphadenectomy and Mediastinoscopic Ultrasound

Abstract

Methods

Results

Comments

Implications for Clinical Practice and Further Research

References

Resection in Stage I/II Non-Small Cell Lung Cancer

Abstract

Surgery in Stages I and II

Conclusion

References

Role of Mediastinal Lymph Node Dissection in Non-Small Cell Lung Cancer

Abstract

Surgical Technique of Systematic Lymph Node Dissection

Role of Nodal Involvement on Survival

Impact of Mediastinal Lymph Node Dissection on Operative Morbidity, Mortality and Quality of Life

Diagnostic Role of Mediastinal Lymph Node Dissection

Therapeutic Role of Mediastinal Lymph Node Dissection

Conclusion

References

Radiation Therapy for Early Stage (I/II) Non-Small Cell Lung Cancer

Abstract

Radiation Therapy alone in Early Non-Small Cell Lung Cancer

Avenues for an Improvement of RT Alone in Early NSCLC

References

Stereotactic Body Radiation Therapy for Early Non-Small Cell Lung Cancer

Abstract

Definitions of Stereotactic Body Radiation Therapy

Staging Procedures before SBRT

Implementation of Techniques in Clinical Routine

Biological Basis of Hypofractionated SBRT

Historical Aspects and Early Clinical Experience in SBRT of Lung Cancer

Clinical Experience

Follow-Up Recommendations

Future

References

Extended Surgical Resection in Stage III Non-Small Cell Lung Cancer

Abstract

Discussion of Stage-Related Treatment

Conclusions

References

Stage III: Definitive Chemoradiotherapy

Abstract

Optimization of Combined Radiotherapy and Chemotherapy

Which Chemotherapy and Radiotherapy Regimens Are Optimal for Concurrent Chemoradiotherapy?

How Do Comorbidities Influence the Performance of Concurrent Chemoradiotherapy?

References

Adjuvant Therapy in Early-Stage Non-Small Cell Lung Cancer

Abstract

Landmark Studies Concerning Adjuvant Platinum-Based Chemotherapy

Negative Studies

The LACE (Lung Adjuvant Cisplatin Evaluation) Meta-Analysis (table 2)

Adjuvant Chemotherapy and Stage (table 3)

Which Chemotherapy Combination?

Adjuvant Radiotherapy

Patient Selection and Predictive or Prognostic Factors

Neoadjuvant Chemotherapy

Conclusion

References

Postoperative Irradiation in Non-Small Cell Lung Cancer

Abstract

References

Altered Fractionation Schemes in Radiotherapy

Abstract

Hypofractionated Stereotactic Body Radiotherapy for NSCLC (Stage I)

Hyperfractionated Accelerated Radiotherapy for Stage III NSCLC

References

Chemotherapy of Advanced Non-Small Cell Lung Cancer

Abstract

Pemetrexed

Cisplatin- vs. Carboplatin-Based Chemotherapy

Elderly Patients and Patients with Reduced Performance Status

Customized Chemotherapy

Targeted Therapies

Maintenance Therapy

Systemic Chemotherapy in Patients Progressing after First-Line Chemotherapy

Assessment of Efficacy

References

Radiotherapy

Abstract

Clinical Manifestations of Advanced Lung Carcinoma

Palliative Potential of Radiotherapy

Treatment Strategies

References

Treatment of Limited Disease Small Cell Lung Cancer

Abstract

Thoracic Radiotherapy

Patient Selection

Future Perspectives

References

Radiochemotherapy in Extensive Disease Small Cell Lung Cancer ED-SCLC

Abstract

RT in ED-SCLC Trial

Future Approaches

Conclusions

References

Radiotherapy for Extensive Stage Small Cell Lung Cancer

Abstract

Introduction

Brain Metastases

Prophylactic Cranial Irradiation

Thoracic Radiotherapy

References

Controversies in the Treatment of Advanced Stages of Small Cell Lung Cancer

Abstract

First-Line Chemotherapy

Prophylactic Cranial Irradiation after First-Line Chemotherapy

Second-Line Chemotherapy

References

Complementary and Alternative Medicinein Lung Cancer Patients: A Neglected Phenomenon?

Abstract

Methods

Results

Discussion

Conclusions

References

Author Index

Subject Index

Back cover

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