Hepatitis C in Renal Disease, Hemodialysis and Transplantation ( Contributions to Nephrology )

Publication series : Contributions to Nephrology

Author: Morales J.M.  

Publisher: S. Karger AG‎

Publication year: 2012

E-ISBN: 9783805598217

P-ISBN(Paperback): 9783805598200

Subject: R512.6 viral hepatitis

Keyword: 外科学,传染病,流行病学与防疫,消化系及腹部疾病,泌尿科学(泌尿生殖系疾病),内科学

Language: ENG

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Description

Hepatitis C virus (HCV) infection is a major health problem worldwide, with currently over 150 million HCV-infected people on the five continents. Although there have been important advances in the diagnosis, prevention and therapy, the infection remains an important health problem in most countries.HCV infection is considered a systemic disease: Not only does it affect the liver, it can induce autoimmune, dermatological and renal disease. Moreover, soon after the discovery of HCV as the major cause of non-A non-B hepatitis, HCV infection was recognized as an important cause and consequence of chronic kidney disease. The publication at hand is an update on the most important topics concerning HCV infection, renal disease and problems with dialysis in the general population as well as in renal transplant patients. Also included is a chapter on the emerging problem of renal complications associated with HCV virus in patients with HIV infection.Containing contributions from a panel of internationally acclaimed experts, this publication is a timely update on HCV infection and the kidney.

Chapter

Preface

Hepatitis C: Epidemiology, Diagnosis, Natural History and Therapy

Abstract

Epidemiology and Diagnosis of HCV Infection

Natural History of HCV Infection

Treatment of HCV Infection

References

Hepatitis C and Renal Disease: Epidemiology, Diagnosis, Pathogenesis and Therapy

Abstract

Epidemiology of Chronic Kidney Disease in Patients with HCV Infection

Diagnosis of Glomerular Diseases Associated with HCV Infection

Pathogenesis of Glomerulonephritis Associated with HCV Infection

Treatment of Glomerular Lesions Associated with HCV Infection

References

Hepatitis C-Induced Renal Disease in Patients with AIDS: An Emergent Problem

Abstract

Introduction

Renal Disease in HIV-Infected Patients

Hepatitis C-Induced Renal Disease in HIV-Infected Patients

Acknowledgement

References

Hepatitis C in Hemodialysis: Epidemiology and Prevention of Hepatitis C Virus Transmission

Abstract

HCV Epidemiology in HD: The 1990s

Routes of Nosocomial HCV Transmission: Lessons from Molecular Virology Papers

Optimal Strategy to Prevent Nosocomial HCV Transmission in HD

Will the HCV Disappear from HD Units?

Current Prevalence of HCV in HD Patients

Attitude when Facing Seroconversion in a Chronic HD Patient

References

Hepatitis C-Related Liver Disease in Dialysis Patients

Abstract

HCV-Related Liver Disease in Dialysis: Biochemical and Clinical Manifestation

Natural History of HCV in Dialysis Population

HCV: Survival and Hemodialysis

HCV: Survival and Peritoneal Dialysis

HCV: Survival and Cardiovascular Disease

HCV: Survival and Quality of Life

Natural History of HCV: Dialysis versus Non-Uremic Controls

HCV Viral Load: Uremic versus Non-Uremic Controls

Histopathology of HCV-Related Liver Disease in Dialysis and Non-Uremic Controls

Kinetics of HCV Load during Hemodialysis

Conclusions

Acknowledgements

References

Treatment of Hepatitis C in Dialysis Patients

Abstract

Prevalence

Natural History of HCV Infection

Treating HCV Infection in the General Population

Justification for Treatment of HCV Infection in Dialysis Patients

Results of Treatment of Chronic HCV Infection in Dialysis Patients: Literature Review

Treatment of Acute HCV Infection in Dialysis Patients

Recommendations for the Treatment of HCV Infection in Dialysis Patients

Interferon Side Effects

References

Selection and Management of Hepatitis C Virus- Infected Patients for the Kidney Transplant Waiting List

Abstract

Screening and Evaluation of Kidney Transplant Candidates for Hepatitis C Virus Infection

Characteristics of Wait- Listed Kidney Transplant Candidates with HCV Infection

Screening Tests

Establishing Liver Disease Severity

Management of HCV-Infected Patients on the Kidney Waiting List

Treatment of HCV in Kidney Transplant Candidates

Conclusions

References

Kidney Transplantation in the Patient with Hepatitis C Virus Infection

Abstract

Influence of HCV Infection on Rejection, Infection and Neoplasia

Impact of HCV Infection on Patient and Graft Survival after Kidney Transplantation

References

Treatment of Hepatitis C Virus Infection after Kidney Transplantation

Abstract

Treatments

References

Immunosuppression in Hepatitis C Virus- Infected Patients after Kidney Transplantation

Abstract

Patient and Graft Survival

Impact of Immunosuppression in HCV-Infected Kidney Transplant Recipients

Optimal Immunosuppressive Regimen in HCV-Infected Kidney Transplant Recipients

Conclusions

References

Impact of Extrahepatic Complications (Diabetes and Glomerulonephritis) Associated with Hepatitis C Virus Infection after Renal Transplantation

Abstract

HCV Infection as Risk Factor for New-Onset Diabetes after Transplantation

HCV-Related Glomerulonephritis in Renal Allografts

Acknowledgments

References

Renal Transplantation from Donors with a Positive Serology for Hepatitis C

Abstract

Transmission of HCV Infection through Kidney Transplantation

Experience with the Transplantation of Kidneys from HCVD+

Suggested Strategies to Decrease HCV Transmission when Transplanting Kidneys from HCVD+

Kidneys from HCVD+: Surplus Organs?

Conclusions

References

Author Index

Subject Index

Cover

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