Description
In this volume of Developments in Ophthalmology, a panel of renowned glaucoma surgeons reports its findings and the updated evidence-based literature data on indications, outcomes, pearls and pitfalls of techniques in which they all have an undisputable ‘hands-on’ everyday experience. The publication begins with chapters on conventional procedures, i.e. trabeculectomy (still the gold standard), deep sclerectomy, and glaucoma drainage device implantation explicitly focusing on postoperative management. The role of the ocular surface in glaucoma surgery and the issue of wound healing and its modulation through antimetabolites are further discussed. In the second part, the attention shifts to new techniques which still have a marginal role, but are promising for particular indications. In the last part, the greatest challenges of glaucoma surgery such as the surgical approach to angle closure, concomitant glaucoma and cataract as well as pediatric glaucoma are discussed in detail. Finally, the last chapter is dedicated to cyclodestructive techniques.This volume is recommended to glaucoma surgeons and glaucoma specialists seeking information on the best therapy for their patients, but also to general ophthalmologists who refer their patients for surgery or follow them up afterwards.
Chapter
Enhanced Trabeculectomy – The Moorfields Safer Surgery System
Prevention of Complications
Glaucoma Drainage Implant Surgery
Glaucoma Drainage Implant Types
Comparison of Glaucoma Drainage Implant Types
Postoperative Management of Penetrating and Nonpenetrating External Filtering Procedures
Key Factors promoting and opposing Filtration
Preventing Complications: The Standard Postoperative Therapy
Recognizing Complications: Key Clinical Variables
Early Complications (Days to Weeks after Surgery)
Mid- Term Complications (Weeks to Months after Surgery)
Late Complications (Months to Years after Surgery)
Ocular Surface and External Filtration Surgery: Mutual Relationships
The Ocular Surface of Glaucomatous Patients
Histopathological Changes of the Conjunctiva in Glaucoma
Impression Cytology Specimens in Glaucoma
Clinical Evidence of Preservative- Induced Conjunctival Impairment
Possible Impact of Benzalkonium Chloride in Deep Ocular Structures
Increased Rate of Glaucoma Surgery Failure
Preoperative Assessment of Failure Risk
Postoperative Changes in the Ocular Surface
Postoperative Evaluation of the Bleb
Wound Healing and Glaucoma Surgery: Modulating the Scarring Process with Conventional Antimetabolites and New Molecules
Wound Healing in Glaucoma Filtration Surgery
Risk Factors for Failure of Glaucoma Filtration Surgery
Mechanism of Action of MMC
Technical Aspects of MMC Administration in Trabeculectomy: Site and Duration of Administration, Concentration and Sustained Delivery
Clinical Results with MMC-Augmented Trabeculectomy
Use of MMC in Tube Surgery and Nonpenetration Glaucoma Filtration Surgery
Mechanism of Action and Administration of 5-FU
Clinical Results with 5-FU-Augmented Trabeculectomy
Complications of Glaucoma Filtration Surgery Augmented with Antimetabolite Use
Needling Revision of Failing Filtration Blebs with MMC or 5-FU Injections
New Molecules for Decreasing Postoperative Scar Formation, and Future Directions of Wound Healing Modulation in Glaucoma Filtration Surgery
Mini-Drainage Devices: The Ex-PRESS Mini-Glaucoma Device
Laser-Assisted Techniques for Penetrating and Nonpenetrating Glaucoma Surgery
Laser-Assisted Techniques for Penetrating Filtering Surgery
Laser Use for Nonpenetrating Filtration Surgery
Ab externo Schlemm’s Canal Surgery: Viscocanalostomy and Canaloplasty
Evaluation of the Aqueous Outflow System
Conclusions and Future Prospects
Ab interno Schlemm’s Canal Surgery: Trabectome and I- Stent
Description of Devices and Procedures
Description of Evidence: Published Results
Surgical Treatment of Angle-Closure Glaucoma
Management of Concomitant Cataract and Glaucoma
Cataract Extraction Alone
Simultaneous or Sequential Cataract and Glaucoma Surgery
Phacoemulsification and Trabeculectomy
New Combined Interventions
Surgical Management of Pediatric Glaucoma
Cyclodestructive Procedures
When Should We Give Up Filtration Surgery: Indications, Techniques and Results of Cyclodestruction
Indications for Transscleral Cyclophotocoagulation and Endoscopic Cyclophotocoagulation
Methods for Transscleral Cyclophotocoagulation and Endoscopic Cyclophotocoagulation