Hypoxia in Pre-Eclampsia: Cause or Effect?

Publisher： Bentham Science Publishers

E-ISSN： 1875-6581|6|4|303-308

ISSN： 1573-4048

Source： Current Women's Health Reviews, Vol.6, Iss.4, 2010-11, pp. : 303-308

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Pre-eclampsia is a pregnancy specific multi-system disorder associated with increased maternal and perinatal morbidity and mortality. In spite of intensive research for several decades into its pathophysiology, the aetiology remains unexplained. There is evidence that maternal tissue blood flow is reduced in pregnancies complicated by this disease, which precedes clinical onset, and persists after delivery. It is however unclear whether the reduced maternal tissue blood flow is associated with changes in tissue oxygenation and/or abnormal tissue oxygen homeostasis and whether this precedes or follows pre-eclampsia. This review examines the cause and effect relationship between hypoxia and pre-eclampsia and possible underlying mechanism(s) of impairment in oxygen regulation.

Related content

Microbiome of the placenta in pre‐eclampsia supports the role of bacteria in the multifactorial cause of pre‐eclampsia

By  

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (ELECTRONIC), Vol. 41, Iss. 5, 2015-05 ,pp. : 662-669 (8)

John Wiley & Sons Inc

Access to resources Recommend Favorite

Increased plasma hyaluronan in severe pre-eclampsia and eclampsia

By Berg S.   Engman A.   Holmgren S.   Lundahl T.   Laurent T. C.  

Scandinavian Journal of Clinical and Laboratory Investigation, Vol. 61, Iss. 2, 2001-04 ,pp. : 131-137 (7)

Informa Healthcare

Access to resources Recommend Favorite

A case of neuropsychiatric effects of pre‐eclampsia / eclampsia

By  

PROGRESS IN NEUROLOGY AND PSYCHIATRY, Vol. 19, Iss. 4, 2015-07 ,pp. : 19-22 (4)

John Wiley & Sons Inc

Access to resources Recommend Favorite

Prediction of pre-eclampsia in early pregnancy

By Rogers Mike S  

Women's Health, Vol. 3, Iss. 5, 2007-09 ,pp. : 571-582 (12)

Future Medicine

Access to resources Recommend Favorite

OC15.05: Fetal myocardial performance index (MPI) in assessing the small‐for‐gestational age (SGA) fetus

By  

ULTRASOUND IN OBSTETRICS & GYNECOLOGY, Vol. 46, Iss. S1, 2015-09 ,pp. : 33-33 (1)

John Wiley & Sons Inc

Access to resources Recommend Favorite