Preparation and Optimization of Moxifloxacin Microspheres for Colon Targeted Delivery Using Quality by Design Approach: In Vitro and In Vivo Study

Publisher: Bentham Science Publishers

E-ISSN: 1875-5704|13|7|1021-1033

ISSN: 1567-2018

Source: Current Drug Delivery, Vol.13, Iss.7, 2016-10, pp. : 1021-1033

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Background: Gut microbiota has a significant role in the pathogenesis ofdiabetes. Colonic microflora modulation using an antibiotic might have an emergingrole to treat the metabolic disorders. The present study was aimed to optimize theMoxifloxacin loaded chitosan microspheres (MCMs) by emulsion cross linkingmethod for colon targeted delivery to alter the microflora.lt;/pgt

Related content