NEW DEVELOPMENTS IN CALCIUM SIGNALING RESEARCH

NEW DEVELOPMENTS IN CALCIUM SIGNALING RESEARCH

Library of Congress Cataloging-in-Publication Data

Contents

Preface

Chapter I The 1,25 DihydroxyvitaminD3-Membrane–Associated, Rapid Response Steroid-Binding Receptor: Physiological Roles and Characterization of Binding Partners

Abstract

Abbreviations

Introduction

Discussion

Major Metabolites of Vitamin D

The 1,25D3-MARRS Receptor: Rapid Responses for Calcium and Phosphate Uptake

Receptor Isolation and Characterisation

Chromatin Immunoprecipitation and Co-Immunoprecipitation Studies

Role of 1,25D3-MARRS Receptor on Select Disease States

Conclusion

Acknowledgments

References

Chapter II Modulation of Airway Epithelial Cell Calcium and Airway Hydration in Cystic Fibrosis: Role of Glucocorticoids and Lipoxins

Abstract

Introduction

Normal Calcium Signalling in Airway Epithelia

Abnormal Calcium Signalling in Cystic Fibrosis

Calcium in Airway Epithelial Inflammation

Anti-Inflammatory Role for Glucocorticoids

Anti-Inflammatory Role for Lipoxin A4

Role of Calcium in Regulating Airway Epithelial Ion Transport and Airway Surface Liquid Dynamics

Anti-Secretory Properties of Glucocorticoids

Pro-Secretory Properties of Lipoxin A4

Pro-Resolution and Pro-Secretory: Therapeutic Perspective for Lipoxin A4

Conclusion

References

Chapter III Excitation–Transcription Coupling: A Quantitative Approach

Abstract

Introduction

Integrative Approach to the Study of Excitation-Transcription Coupling

Elucidation of CREB Signaling Microdomains by Wavelet Transform Analysis

Excitation-Transcription Coupling Signaling

Conclusion

References

Chapter IV A Novel Concept on the Repetitive Calcium Elevation

Abstract

Introduction

References

Chapter V Calcium Binding Proteins in the Liver Fluke, FASCIOLA HEPATICA

Abstract

Introduction: FASCIOLA HEPATICA and its Significance

FASCIOLA HEPATICA CALCIUM BINDING PROTEINS

Conclusion

References

Chapter V IRole of Regucalcin in Calcium Signaling of Kidney Cells

Abstract

Introduction

Horonal Regulation of Regucalcin Gene Expression

Regucalcin Regulates Intracellular Calcium Homeostasis

Regucalcin Regulates Signaling Pathway-Related Enzyme Activity

Regucalcin Regulates Nuclear Function

Role of Regucalcin in Proximal Tubular Epithelial Cells

Involvement of Regucalcin in Kidney Disorder

Conclusion

References

Chapter VII Suppressive Role of Regucalcin in Cell Protein Synthesis: Involvement in Calcium Signaling

Abstract

Introduction

Role of Regucalcin in Nuclear Regulation

Regucalcin Suppresses Protein Synthesis

Regucalcin Stimulates Protein Degradation

Conclusion

References

Index