ESOPHAGEAL CANCER: SYMPTOMS, MANAGEMENT AND PROGNOSIS

ESOPHAGEAL CANCER: SYMPTOMS, MANAGEMENT AND PROGNOSIS

Library of Congress Cataloging-in-Publication Data

Contents

Preface

Chapter 1: Epidemiology and Screening of Esophageal Cancer

Abstract

Generalities

Incidence

Screening

Conclusion

References

Chapter 2: Genetic and Epigenetic Events in the Molecular Pathology of Esophageal Cancer

Abstract

Introduction

Key Molecular Aspects

Cellular Proliferation and Death

DNA Maintenance

Cell Signalling

RNA Alterations – miRs, Long Noncoding RNAs

Potential Clinical Applications

References

Chapter 3: Anesthetic Management for Esophagectomy

1. Abstract

2. Introduction

3. Anesthetic Considerations

Conclusion

References

Chapter 4: Staging of Esophageal Cancer

Abstract

Introduction

CT-Scan

Endoscopic Ultrasonography (EUS/EUS-FNA)

PET-CT-Scan

Bronchoscopy: Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA)

Magnetic Resonance Imaging (MRI)

Ultrasonography

Contrast Radiography

Laparoscopy-Thoracoscopy: Surgical Staging

Response to Therapy: Re-Staging

Conclusion

References

Chapter 5: Early Esophageal Cancer

Abstract

Introduction

Definition

Barrett’s Esophagus and High Grade Dysplasia

Diagnosis

Treatment of Early Esophageal Cancer

Endoscopic Approaches

Conclusion

References

Chapter 6: Surgical Treatment for Esophageal Cancer

Abstract

Introduction

Patient Selection

Surgical Treatment

Morbidity

Conclusion

References

Chapter 7: Postoperative Complications in Esophageal Surgery

Abstract

Introduction

General Complications

Specific Complications

Mortality

Conclusion

References

Chapter 8: Neoadjuvant and Adjuvant Treatment of Resectable Esophageal Cancer

Abstract

Introduction

Postoperative Adjuvant Treatment

Conclusion

References

Chapter 9: Definitive Chemoradiotherapy in Esophageal Cancer

Abstract

1. Introduction

2. Adenocarcinoma or Squamous Cell Carcinoma of the Esophagus

3. Definitive CRT as a Treatment Strategy: Definitive CRT versus Definitive Radiotherapy

4. Definitive CRT versus Neoadjuvant CRT Followed by Surgery

5. Optimal CRT Schedule

6. Salvage Surgery after Definitive CRT

References

Chapter 10: Palliative Treatment of Esophageal Cancer

Abstract

Introduction

Endoscopic Relief of Luminal Obstruction

Radiotherapy or Combination Chemoradiotherapy

Endoscopic Techniques

Nutritional Support

References

Editors’ Contact Information

Index