Chapter
Role of ATP and Chromogranins in the Storage of Catecholamines
Role of Membrane Proteins in the Uptake of Catecholamines - Evidence for Amine Transport Utilizing Membrane ATPase and an amine carrier
Biosynthesis of Catecholamines
CHAPTER 3. NERVE GROWTH FACTOR
CHAPTER 4. TASTE RECEPTOR PROTEINS
Proteins Characteristic of Taste Buds
CHAPTER 5. THE ROLE OF CYCLIC NUCLEOTIDES IN VISUAL EXCITATION
CHAPTER 6. THE ACETYLCHOLINE RECEPTOR: PROGRESS REPORT
CHAPTER 7. REGULATION OF TRYPTOPHAN AND TYROSINE HYDROXYLASE
PURIFICATION AND PROPERTIES OF TYROSINE AND TRYPTOPHAN HYDROXYLASE
REGULATION OF ENZYME LEVELS
IN VIVO REGULATION OF HYDROXYLASE ACTIVITY
CHAPTER 8. SERUM DOPAMINE 3-HYDR0XYLASE AS AN INDEX OF SYMPATHETIC FUNCTION
Sources and Turnover of Serum DBH in Animals
Assays of Human Serum DBH
Human Serum DBH Activity in Normal and Disease States
Serum DBH Changes in Disease States
CHAPTER 9. POSSIBILITIES FOR DRUG DEVELOPMENT BASED ON THE CYCLIC AMP SYSTEM
I. AGENTS ALTERING THE INTRACELLULAR LEVELS OF THE CYCLICNUCLEOTIDES:
II. AGENTS ALTERING THE INTRACELLULAR ACTIVITY OF CYCLIC NUCLEOTIDES:
CHAPTER 10. REGULATION OF PHOSPHORYIASE b TO a CONVERSION IN MUSCLE
Catecholamine-Stimulated Phosphorylase b to a Conversion
Phosphorylase b to a Conversion in Cardiac Muscle
Conversion of Phosphorylase b to a in Smooth Muscle
The Role of Ca2+ in the Regulation of Phosphorylase b to a Conversion in Muscle
The Regulation of Phosphorylase a Production in Muscle by Factors Other than Ca 2+
CHAPTER 11. SYMPATHETIC REGULATION OF THYROID HORMONE SECRETION
CHAPTER 12. ROLE OF CYCLIC AMP IN THE ACTION OF ANTIDIURETIC
CHAPTER 13. TRANS-SYNAPTIC ENZYME INDUCTION
Trans-synaptic Induction of Tyrosine Hydroxylase
Specificity of Trans-synaptic Induction
Relationship between Duration of Increased Neuronal Activity and Time Requirement for the Single Steps of Enzyme Induction
First and Second Messenger of Trans-synaptic Induction
Trans-synaptic Enzyme Induction as a Long-term Adaptation to Increased Transmitter Utilization
Importance of Trans-synaptic Regulation for Growth and Development of the Peripheral Sympathetic Nervous System
CHAPTER 14. DO CYCLIC NUCLEOTIDES PROMOTE THE TRANS-SYNAPTIC INDUCTION OF TYROSINE HYDROXYLASE?
NICOTINIC RECEPTORS AND CYCLIC NUCLEOTIDES OF ADRENAL MEDULLA
TRANS-SYNAPTIC INDUCTION OF TH IN ADRENAL MEDULLA: INVOLVEMENT OF CYCLIC NUCLEOTIDES
ADRENAL DEMEDULLAT1ON: A MODEL TO STUDY TRANS-SYNAPTIC CONTROL OF TH ACTIVITY IN SYMPATHETIC GANGLIA
INDUCTION OF TH ACTIVITY IN SYMPATHETIC GANGLIA OF ADRENAL DEMEDULLATED RATS: INVOLVEMENT OF CYCLIC NUCLEOTIDES
Discovery and Partial Purification of Substance P
The Isolation of a Sialogogic Peptide; its Characterization as Substance P
Radioimmunoassay For Substance P
Physiological Roles of Substance P
CHAPTER 16. TO SPRITZ OR NOT TO SPRITZ: THE DOUBTFUL VALUE OF AIMLESS IONTOPHORESIS
PHARMACOLOGIC CONSIDERATIONS
ACTIONS OP CATECHOLAMINES IN THE NERVOUS SYSTEM
CHAPTER 17. THE USE OF AUTORADIOGRAPHIC TECHNIQUES FOR THE IDENTIFICATION AND MAPPING OF TRANSMITTER-SPECIFIC NEURONES IN THE BRAIN
CHAPTER 18. NEUROTRANSMITTER UPTAKE: A TOOL IN IDENTIFYING NEUROTRANSMITTERS-SPECIFIC PATHWAYS
Brief Review of the Literature
CHAPTER 19. REGULATION OF SEROTONIN SYNTHESIS
Role of Tryptophan in the Regulation of 5-HT Synthesis
Rate of Tryptophan Hydroxylation :a A second regulatory Factor of 5-HT Synthesis
CHAPTER 20. SOME FACTORS IN THE REGULATION OF CENTRAL SEROTONERGIC SYNAPSES
The Biochemical Anatomy of the Serotonergic System in the Brain
Factors Influencing the Supply of SubstrateTo the Presynaptic Biosynthetic Apparatus
Regulation of the Activity or Amount of Tryptophan Hydroxylase in Brain
A Degradative Process for 5-HT That May be Related to Synaptic Function
CHAPTER 21. NEUROCHEMICAL CORRELATES OF SYNAPTICALLY ACTIVE AMINO ACIDS
CHAPTER 22. THE ROLE OF CALCIUM IN THE CENTRAL EFFECTS OF BIOGENIC AMINES
Biogenic Amines in the•Cerebral Cortex
The Action of Calcium on Cortical Neurones
Metallic Cations and Cerebral Neurones
Studies with Calcium Antagonists
CHAPTER 23. ANOTHER LOOK AT THE MONOAMINE OXIDASES AND THE MONOAMINE OXIDASE INHIBITOR DRUGS
SEPARATION OF MULTIPLE FORMS OF MAO BY ELECTROPHORESIS
THE USE OF SELECTIVE SUBSTRATES AND DRUGS TO DEMONSTRATE MULTIPLE FORMS OF MAO
SOME PROPERTIES OF THE MAO'S
LOCALIZATION OF THE MAO'S
THE CONSEQUENCES OF ADMINISTERING SPECIFIC MAO INHIBITOR DRUGS ON AMINE METABOLISM IN BRAIN
CHAPTER 24. THE ROLE OF CATECHOLAMINES AND ACETYLCHOLINE IN THE REGULATION OF ENDOCRINE FUNCTION
Kidney: Juxtaglomerular Cells
Kidney: Erythrogenin-Secreting Cells
Pancreatic Islets: g Cells
Pancreatic Islets: a Cells
Calcitonin-Secretins and Gastrointestinal Endocrine Cells.
Control of Thyroid. Adrenocorticoid and Gonadal Secretion
Hypothalamic Control of Anterior Pituitary Secretion
Intermediate Lobe of the Pituitary
Posterior Pituitary Secretion
CHAPTER 25. THE NEUROENDOCRINOLOGY OF HUMAN SLEEP
Adrenocorticotropic Hormone (ACTH
Gonadotropins and Testosterone
Thyroid Stimulating Hormone (TSH)
Chapter 26. Role of Brain Monoamines in Male Sexual Behavior
Effect of PCPA on the sexual behavior of the male rat
Effect of PCPA on the sexual behavior of other animal species.
Role of testosterone and other hormones in the PCPA effect,.
Effect of reserpine and tetrabenazine.
Brain catecholamines and sexual behavior.
CHAPTER 27. AREA POSTREMA: CHEMORECEPTOR TRIGGER ZONE FOR VOMITING - IS THAT ALL?
Topology of the area postrema.
Ultrastructural features and barrier properties.
Nerve cells, fibers and humors
Vomiting and other functions of AP
CHAPTER 28. NORADRENERGIC MEDIATION OF TRAUMATIC SPINAL CORD AUTODESTRUCTION1'2
The Norepinephrine Hypothesis About Hemorrhagic Necrosis of Severe Spinal Cord Injury
Catecholamine Spinal Vascular Ennervation
Supporting Experimental Evidence For The NE Spinal Injury Hypothesis
CHAPTER 29. THE MECHANISMS OF ACTION OF L-DOPA IN PARKINSON'S DISEASE
I. L-dopa as a Dopamine replenishing drug
II. L-Dopa Therapy and Displacement of Brain Serotonin
III. 3-0-Methyl-Dopa - Depot Source for Dopamine
IV. The Role of Norepinephrine
V. Condensation Products of Dopamine And the Antiparkinson Action of L-Dopa
VI. Some Clinico-Pharmacological Problems Related to L-Dopa Therapy
CHAPTER 30. SOME SPECULATIONS CONCERNING A POSSIBLE BIOCHEMICAL BASIS OF MINIMAL BRAIN DYSFUNCTION
The extent of the minimal brain dysfunction syndrome
A Possible Biochemical Basis for M B D
CHAPTER 31. BRAIN MECHANISMS IN MOTOR CONTROL
1, The Cerebral Motor Cortex
2. The Cerebellum and the Basal Ganglia
4. Outlook for Future Research
CHAPTER 32. MOLECULAR CODING OF MEMORY
Chemical Correlates of Learning and Memory
Validity of the Bioassay Approach
Chemical Properties of the Active Substances
Specificity of the Behavioral Bioassays
Is a molecular code necessary?
CHAPTER 33. THE BIOCHEMICAL BASIS OF LEARNING AND MEMORY
CHAPTER 34. OPIATE RECEPTORS
Structure-Activity Relationships
Attempts to Localize Receptors in Tissues
Progress in Receptor Purification
Other Binding Studies with Membrane Fragments
Minireviews of the Neurosciences from Life Sciences
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