Nutrition, Digestion, Metabolism :Proceedings of the 28th International Congress of Physiological Sciences, Budapest, 1980

Publication subTitle :Proceedings of the 28th International Congress of Physiological Sciences, Budapest, 1980

Author: Gáti   T.;Szollár   L. G.;Ungváry   Gy.  

Publisher: Elsevier Science‎

Publication year: 2013

E-ISBN: 9781483189970

P-ISBN(Paperback): 9780080268255

P-ISBN(Hardback):  9780080268255

Subject: R Medicine and Health

Language: ENG

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Description

Advances in Physiological Sciences, Volume 12: Nutrition, Digestion, Metabolism covers the proceedings of the 28th International Congress of Physiological Sciences, held in Budapest in 1980, which mainly focuses on human nutrition, digestion, and metabolism.
This compilation is divided into eight parts. This text first gives an introduction to vitamins and trace elements, including its role, effects, and influences on human biological processes. This book then explains the role of cyclic nucleotides in stimulus—secretion coupling of exocrine glands and the physiological components of the gastric mucosal barrier, along with their role in mucosal defense. Motility in control of gastric emptying; intestinal polypeptides and peptidergic nerves; and molecular changes during metabolic processes of gastrointestinal peptide hormones are also tackled. This text also introduces the factors involved in the integrated mechanism of intestinal absorption. This book concludes by explaining the lipoprotein metabolism, apolipoproteins, and lipid constituents.
This publication will be invaluable to those in the field of physiological sciences interested specifically in studying human nutrition, digestion, and metabolism.

Chapter

Microclimate of the cell, pericellular medium and unstirred layer (10, 14)

Conclusion

References

PART 1: VITAMINS AND TRACE ELEMENTS

CHAPTER 3. INTRODUCTION TO VITAMINS AND TRACE ELEMENTS

CHAPTER 4. DIETARY VITAMIN D, SUNLIGHT AND THE CAUSE OF RICKETS

References

CHAPTER 5. PHOSPHATE INFLUX ACROSS THE MUCOSAL BORDER OF RABBIT SMALL INTESTINE. EFFECT OF1,25-DIHYDROXYCHOLECALCIFEROL

BRUSH BORDER INFLUX OF PHOSPHATE

EFFECT OF 1,25(OH) 2D3 ON THE PHOSPHATE INFLUX IN DUODENUM

CONCLUSIONS

ACKNOWLEDGEMENTS

REFERENCES

CHAPTER 6. INTERACTIONS BETWEEN MAGNESIUM AND 1.25 DIHYDROXYCHOLECALCIFEROL IN UREMIC RATS

Introduction

Material and Methods

Results

Discussion

Conclusions

References

CHAPTER 7. EFFECTS OF MILD AND SEVERE RENAL INSUFFICIENCY ON THE CALCIUM TRANSPORT OF THE RAT ILEUM IN VITRO

References

CHAPTER 8. SOME EFFECTS OF CADMIUM ON CALCIUM METABOLISM IN RATS

MATERIALS AND METHODS

RESULTS AND DISCUSSION

REFERENCES

CHAPTER 9. ZINC AND CADMIUM METALLOPROTEIN INDUCED BY CADMIUM ADMINISTRATION

INHIBITION OF GROWTH AND 35S04- INCORPORATION

CADMIUM INDUCTION OF Cd-Zn-METALLOTHIONEIN

PROTEIN EXTRACTION

PROTEIN PURIFICATION

DISCUSSION

ACKNOWLEDGEMENT

REFERENCES

CHAPTER 10. SOME KINETIC ASPECTS OF ASCORBIC ACID IN MAN

References

CHAPTER 11. THE ROLE OF ASCORBIC ACID IN LIPID METABOLISM AND ATHEROGENESIS

INTRODUCTION

THE ROLE OF ASCORBIC ACID IN CHOLESTEROL METABOLISM

PATHOLOGICAL CONSEQUENCES OF CHRONIC MARGINAL AA-DEFICIENCY

HYPOCHOELESTEROLENIC EFFECTS OF AA IN MAN

SYNERGISM BETWEEN AA AND PECTIN

CONCLUSIONS

REFERENCES

CHAPTER 12. INFLUENCE OF RIBOFLAVIN DEFICIENCY ON INTESTINAL DRUG METABOLIZING ENZYME ACTIVITIES IN RAT

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 13. INFLUENCE OF PROTEIN, IRON AND COPPER LEVEL IN THE DIET ON DYNAMICS OF DIGESTION IN DUODENUM

References

CHAPTER 14. THE INTERACTION BETWEEN CHROMIUM AND INSULIN

INTERACTION BETWEEN CHROMIUM AND INSULIN IN VIVO

REFERENCES

CHAPTER 15. CONCLUDING REMARKS ON VITAMINS AND TRACE ELEMENTS

PART 2: ROLE OF CYCLIC NUCLEOTIDES IN STIMULUS-SECRETION COUPLING OF EXOCRINE GLANDS

CHAPTER 16. ORIGIN AND POSSIBLE ROLE OF CYCLIC GMP AND CYCLIC AMP IN RAT AND GUINEA PIG PANCREATIC ACINAR CELLS

1. POSTULATED RELATION OF PANCREATIC SECRETAGOGUES WITH CYCLIC NUCLEOTIDE

2. THE CANDIDACY OF THE PHOSPHATIDYLINQSITOL-PHOSPHATIDIC ACID EFFECT AS AN EFFECTOR OF PANCREOZYMIN, BOMBESIN, AND ACETYLCHOLINE

3. THE ROLE OF INTRA- AND EXTRACELLULAR CALCIUM IN ACTIVATING ACINAR CEIL FUNCTIONS

4. THE CYCLIC GMP SYSTEM

5. ROLE OF GUANYL NUCLEOTIDES IN HORMONE-EFFECTOR COUPLING IN PANCREATIC PLASMA MEMBRANES

6. PANCREOZYMIN RECEPTORS

7. RECEPTORS FOR SECRETIN AND VASOACTIVE INTESTINAL PEPTIDE (VIP)

8. CONVERGENCE AND INTERACTION OF THE EFFECTS OF THE TWO GROUPS OF SECRETAGOGUES ON RAT AND GUINEA PIG PANCREATIC ACINAR CELLS

9. SPARE RECEPTORS FOR PANCREATIC SECRETAGOGUES

10. REGULATION OF THE NUMBER OF ACTIVE HORMONE RECEPTORS. DESENSITIZATION MECHANISMS

11. CONCLUSIONS

ACKNOWLEDGMENTS

REFERENCES

CHAPTER 17. ELECTROPHYSIOLOGICAL STUDIES ON THE ROLE OF CYCLIC GMP IN PANCREATIC ACINAR CELL STIMULUS-SECRETION COUPLING

INTRODUCTION

SECRETAGOGUE-EVOKED DEPOLARIZATIONS

THE ROLE OF INTRACELLULAR Ca

THE EFFECT OF CYCLIC GMP

GENERAL CONCLUSIONS

REFERENCES

CHAPTER 18. STIMULUS-SECRETION COUPLING INPERIFUSED IMMOBILIZED ACINI FROM RAT PANCREAS

SUMMARY

INTRODUCTION

METHODS

RESULTS AND DISCUSSION

ACKNOWLEDGEMENT

REFERENCES

CHAPTER 19. THE POSSIBLE ROLE OF CYCLIC AMP AS A SECOND MESSENGER IN PANCREATIC DUCT CELLS

1. INTRODUCTION

2. METHODS

3. RESULTS

4. DISCUSSION

5. CONCLUSION

6. REFERENCES

CHAPTER 20. cAMP AND SECRETAGOGUE INTERACTIONS IN ISOLATED GASTRIC GLANDS

Introduction

Methods

Results and Discussion

Summary

ACKNOWLEDGEMENT

REFERENCES

CHAPTER 21. FEED-BACK MECHANISM SYSTEMS BETWEEN THE ATP-ADENYLATE CYCLASE-cAMP AND ATP-Na+-K+-DEPENDENT ATP-ASE-ADP IN THE RAT AND HUMAN GASTRIC FUNDIC MUCOSA IN RELATION TO GASTRIC ACID SECRETION

MATERIALS and METHODS

RESULTS

DISCUSSION

ABSTRACT

REFERENCES

CHAPTER 22. PEPTIDERGIC REGULATION OF THE CYCLIC AMP SYSTEM IN THE INTESTINAL EPITHELIUM

ACKNOWLEDGMENTS

REFERENCES

CHAPTER 23. INTERACTION OF SECRETAGOGUES, BILE ACIDS AND LAXATIVES WITH ENZYMES OF CYCLIC AMP METABOLISM FROM HUMAN INTESTINAL MUCOSA

SUMMARY

INTRODUCTION

METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 24. STIMULATORY PATHWAYS IN THE REGULATION OF GASTRIC ACID SECRETION

INTRODUCTION

METHOD

RESULTS and DISCUSSION

CONCLUSION

SUMMARY

REFERENCES

CHAPTER 25. CONCLUDING REMARKS ON ROLE OF CYCLIC NUCLEOTIDES IN STIMULUS-SECRETION COUPLING OF EXOCRINE CELLS

PART 3: PHYSIOLOGICAL COMPONENTS OF THE GASTRIC MUCOSAL BARRIER AND THEIR ROLE IN MUCOSAL DEFENSE

CHAPTER 26. INTRODUCTION TO THE PHYSIOLOGICAL COMPONENTS OF THE GASTRIC MUCOSAL BARRIER AND THEIR ROLE IN MUCOSAL DEFENSE

REFERENCES

CHAPTER 27. GASTRIC MUCOSAL BICARBONATE PRODUCTION

ABSTRACT

INTRODUCTION

TECHNIQUES FOR MEASURING GASTRIC HCO3

PROPERTIES OF GASTRIC HCO3 TRANSPORT

DISCUSSION

REFERENCES

CHAPTER 28. ALKALINE SECRETION BY THE CANINE HEIDENHAIN POUCH IN RESPONSE TO EXOGENOUS ACID, SOME GASTROINTESTINAL HORMONES AND PROSTAGLANDIN

SUMMARY

INTRODUCTION

METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 29. EFFECT OF GASTRIC MUCOSAL BARRIER BREAKERS ON CANINE ALKALINE SECRETION AND TRANSMUCOSAL POTENTIAL DIFFERENCE

MATERIAL AND METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 30. THE STRUCTURE AND PROPERTIES OF GASTRIC MUCUS

REFERENCES

CHAPTER 31. SECRETIN STIMULATION OF GASTRIC MUCUS SECRETION IN THE CAT: THE VISCOSITY OF GASTRIC JUICE IN RELATION TO GLYCOPROTEIN STRUCTURE AND CONCENTRATION

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

ACKNOWLEDGEMENTS

REFERENCES

CHAPTER 32. LOSS OF HYDROGEN IONS IN DIFFERENT PARTS OF THE NON-STIMULATED STOMACH

References

CHAPTER 33. THE EFFECT OF DRUGS AFFECTING ADRENERGIC MECHANISM ON THE GASTRIC TRANSMUCOSAL POTENTIAL DIFFERENCEIN RATS

SUMMARY

INTRODUCTION

MATERIALS AND METHODS

RESULTS

CONCLUSIONS

AKCNOWLEDGEMENTS

REFERENCES

CHAPTER 34. SOURCES OF THE POSITIVE POTENTIAL DIFFERENCE ACROSS THE IN VITRO FROG STOMACH IN CI-FREE MEDIA

INTRODUCTION

METHODS

RESULTS AND DISCUSSION

CONCLUSIONS

REFERENCES

CHAPTER 35. EFFECTS OF OUABAIN ON IN VITRO FROG STOMACH

INTRODUCTION

METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 36. Ca ++ CONTROLLED GASTRIC H+/K+ PUMP: SITE OF SCN- ACTION

INTRODUCTION

METHODS

RESULTS AND DISCUSSION

REFERENCES

CHAPTER 37. CONCLUDING REMARKS ON THE PHYSIOLOGICAL COMPONENTS OF THE GASTRIC MUCOSAL BARRIER AND THEIR ROLE IN MUCOSAL DEFENSE

PART 4: MOTILITY IN CONTROL OF GASTRIC EMPTYING

CHAPTER 38. INTRODUCTION TO MOTILITY IN CONTROL OF GASTRIC EMPTYING

CHAPTER 39. CONTROL OF THE MYOELECTRIC COMPLEX OF THE STOMACH AND SMALL INTESTINES BY THE INTRINSIC NERVOUS SYSTEM

REFERENCES

CHAPTER 40. ELECTRIC ACTIVITY OF FORESTOMACH SMOOTH MUSCLES IN SHEEP AFTER INFUSION OF AMMONIUM CHLORIDE AND ALPHA AND BETA ADRENERGIC RECEPTORS BLOCKADE

SUMMARY

THE AIM OF THE WORK

INTRODUCTION

MATERIALS AND METHODS

RESULTS

REFERENCES

CHAPTER 41. MICROELECTRODE STUDIES ON SINGLE SMOOTH MUSCLE CELLS OF THE FUNDUS BEFORE AND AFTER FUNCTIONAL LOADING

METHODS

RESULTS

DISCUSSION

REFERENCES

PART 5: INTESTINAL POLYPEPTIDES AND PEPTIDERGIC NERVES

CHAPTER 42. INTRODUCTION TO INTESTINAL POLYPEPTIDES AND PEPTIDERGIC NERVES

CHAPTER 43. INTESTINAL POLYPEPTIDES AND PEPTIDERGIC NERVES

REFERENCES

CHAPTER 44. CHOLECYSTOKININ OCTAPEPTIDE: PUTATIVE NEUROTRANSMITTER IN THE GUT

IDENTITY AND ORIGINS

ACTIONS OF CCK8 IN THE ENTERIC NERVOUS SYSTEM

PHYSIOLOGICAL IMPLICATIONS

CHAPTER 45. ROLE OF OPIATE PEPTIDES IN THE REGULATION OF GASTROINTESTINAL MUTILITY AND SECRETION

OPIATE RECEPTORS AND OPIATE PEPTIDES

BIOLOGICAL ACTIONS

SUMMARY

REFERENCES

CHAPTER 46. ENTEROGASTRONE CANDIDATES AMONG THE GASTROINTESTINAL POLYPEPTIDES

INTRODUCTION

ENTEROGASTRONE CANDIDATES

NEUROTENSIN

SUMMARY

REFERENCES

CHAPTER 47. EFFECT OF INTRALUMINAL pH ON THE RELEASE OF GASTRIN AND SOMATOSTATIN FROM THE ANTROPYLORIC REGION.THE POSSIBLE ROLE OF SOMATOSTATIN AS AN INHIBITORY HORMONE OF GASTRIC ACID SECRETION

REFERENCES

CHAPTER 48. CAPSAICIN-SENSITIVE INNERVATION OF THE INTESTINE

INTRODUCTION

METHODS

RESULTS

DISCUSSION

CONCLUSION

REFERENCES

CHAPTER 49. EFFECTS OF AMINO ACIDS AND DISACCHARIDES ON AFFERENT NERVE DISCHARGE FROM RAT SMALL INTESTINE IN VIVO

Introduction

Methods

Results

Discussion

References

CHAPTER 50. CONCLUDING REMARKS ON INTESTINAL POLYPEPTIDES AND PEPTIDERGIC NERVES

PART 6: MOLECULAR CHANGES DURING METABOLIC PROCESSES OF GASTROINTESTINAL PEPTIDE HORMONES

CHAPTER 51. INTRODUCTION TO MOLECULAR CHANGES DURING METABOLIC PROCESSES OF GASTROINTESTINAL PEPTIDE HORMONES

CHAPTER 52. THE ROLE OF CYCLIC NUCLEOTIDES IN PANCREATIC BICARBONATE SECRETION STIMULATED BY SECRETIN AND VIP

Calcium ions

Cyclic AMP

Cyclic GMP

Synopsis

References

CHAPTER 53. MOLECULAR CONFORMATION INFLUENCE ON TRANSPORT PROCESSES AND RECEPTOR BINDING OF GASTRIN; A NEW SCHEME OF GASTRIC SECRETORY REGULATION

CHAPTER 54. METABOLISM OF DIFFERENT MOLECULAR FORMS OF CHOLECYSTOKININ

1. CCK-8-destroying activities of different tissue homogenates

2. CCK-33 and CCK-8-destroying activities of kidney cortex homogenate

3. Inhibition pattern of CCK-destroying enzyme

CHAPTER 55. CATABOLIC PATHWAYS OF THE C-TERMINAL PENTAPEPTIDE OF GASTRIN (PENTAGASTRIN)

REFERENCES

CHAPTER 56. NERVOUS REGULATION OF THE HORMONE SECRETION

METHOD

BIOLOGICAL METHOD

REFERENCES

CHAPTER 57. CONCLUDING REMARKS ON MOLECULAR CHANGES DURING METABOLIC PROCESSES OF GASTROINTESTINAL PEPTIDE HORMONES

PART 7: FACTORS INVOLVED IN THE INTEGRATED MECHANISM OF INTESTINAL ABSORPTION

CHAPTER 58. INTRODUCTION TO FACTORS INVOLVED IN THE INTEGRATED MECHANISM OF INTESTINAL ABSORPTION

CHAPTER 59. INTESTINAL ABSORPTION STUDIED BY VASCULAR PERFUSION

WHY VASCULAR PERFUSION?

THE VASCULARLY PERFUSED PREPARATION

METHODS FOR STUDYING ABSORPTION USING VASCULARLY PERFUSED INTESTINE

USE OF THE VASCULARLY PERFUSED INTESTINE TO STUDY THE EXIT STEP OF ABSORPTION

COMPETITION FOR EXIT

A MODEL FOR TRANSEPITHELIAL TRANSFER: EFFECT OF ALTERING THE EXIT RATE CONSTANT

ACKNOWLEDGEMENTS

REFERENCES

CHAPTER 60. SIGNIFICANCE OF THE COUNTERCURRENT MECHANISM IN INTESTINAL ABSORPTION

REFERENCES

CHAPTER 61. ENDOCRINE INFLUENCE ON ABSORPTION

GASTRIN

SECRETIN

VASOACTIVE INTESTINAL POLYPEPTIDE /VIP/

VIP-SECRETING TUMORS

INSULIN

GLUCAGON

GLUCAGON EFFECT ON INTESTINAL WATER AND ELECTROLYTE MOVEMENTS

EFFECT OF GLUCAGON ON SUGAR TRANSPORT IN VITRO

EFFECT OF GLUCAGON ON SUGAR ABSORPTION IN VIVO

EFFECT OF GLUCAGON ON PORTAL GLUCOSE TRANSPORT

CHANGES OF MUCOSAL CAMP AND cGMP LEVELS AFTER GLUCAGON ADMINISTRATION

GENERAL REMARKS ON THE EFFECT OF G-I HORMONES ON INTESTINAL PERMEATION

REFERENCES

CHAPTER 62. INTESTINAL ABSORPTION IN MAN

REFERENCES

CHAPTER 63. THE INFLUENCE OF SURGICAL AND CHEMICAL INHIBITION OF DIGESTIVE ENZYMES ON THE ABSORPTION OF FOREIGN PROTEIN IN RATS

MATERIALS AND METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 64. VITAMIN B-12 ABSORPTION IN GNOTOBIOTIC DOGS AND CECECTOMIZED GNOTOBIOTIC RATS

INTRODUCTION AND BACKGROUND

METHODS

SUMMARY AND CONCLUSIONS

ACKNOWLEDGEMENTS

REFERENCES

CHAPTER 65. MECHANISMS INVOLVED IN SMALL INTESTINAL TRANSPORT OF CALCIUM AND PHOSPHATE IONS: STUDIES WITH ISOLATED PLASMA MEMBRANE VESICLES

Na-Pi.-cotransport system in the brush border membrane

Influence of 1,25-(OH) -vitamin D3 on the Na-Pi-cotransport system

A model of transcellular Ca-transport

ATP-driven Ca-transport in basal-lateral plasma membranes

Inhibition of ATP driven Ca -transport by Na

Stimulation of Ca-efflux by a Na-gradient (out>in)

Conclusions

References

CHAPTER 66. THE ROLE PLAYED BY THE STOMACH IN THE RATE OF GLUCOSE ABSORPTION IN THE RAT

SUMMARY

INTRODUCTION

METHOD

RESULTS

DISCUSSION

ACKNOWLEDGEMENTS

REFERENCES

CHAPTER 67. CARRIER-MEDIATED UPTAKE OF SUGARS THROUGH THE BASOLATERAL MEMBRANE OF COLON EPITHELIUM

INTRODUCTION

METHODS

RESULTS AND DISCUSSION

SUMMARY

REFERENCES

CHAPTER 68. PLASMA LIPID CURVES AFTER LONG AND MEDIUM CHAIN TRIGLYCERIDE ABSORPTION ON PATIENTS WITH DECREASED PANCREAS LIPASE ACTIVITY

INTRODUCTION

MATERIALS AND METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 69. CONCLUDING REMARKS ON FACTORS INVOLVED IN THE INTEGRATED MECHANISM OF INTESTINAL ABSORPTION

PART 8: LIPOPROTEIN METABOLISM, APOLIPOPROTEINS, LIPID CONSTITUENTS

CHAPTER 70. INTRODUCTION TO LIPOPROTEIN METABOLISM, APOLIPOPROTEINS, LIPID CONSTITUENTS

CHAPTER 71. LIPOPROTEINS OF BIOLOGICAL FLUIDS

ACKNOWLEDGEMENTS AND NOTICE OF GRANT SUPPORT

REFERENCES

CHAPTER 72. REGULATION OF LIPOPROTEIN SYNTHESIS IN CULTURED HEPATOCYTES

INTRODUCTION

MATERIALS AND METHODS

RESULTS

CHARACTERIZATION OF NEWLY SECRETED VLDL

DISCUSSION

REFERENCES

CHAPTER 73. CHYLOMICRON METABOLISM

ACKNOWLEDGEMENTS

REFERENCES

CHAPTER 74. CELL RECEPTOR AND ANTIBODY BINDING DOMAINS OF APOLIPOPROTEIN B ARE NOT IDENTICAL

INTRODUCTION

METHODS

RESULTS

DISCUSSION

REFERENCES

CHAPTER 75. THE LIPOPROTEIN Lp(a): STRUCTURE, METABOLISM AND SIGNIFICANCE FOR VASCULARY DISEASES

INTRODUCTION

STRUCTURE AND COMPOSITION OF Lp(a)

THE SIGNIFICANCE OF Lp(a) FOR CARDIOVASCULAR DISEASES

THE METABOLISM OF Lp(a)

REFERENCES

CHAPTER 76. THE COMPOSITION OF TRIACYLGLYCEROLS INHUMAN BLOOD LIPOPROTEINS, MILK AND ADIPOSE TISSUE

SUBJECTS

METHODS

RESULTS AND DISCUSSION

SUMMARY

REFERENCES

CHAPTER 77. CONCLUDING REMARKS ON LIPOPROTEIN METABOLISM, APOLIPOPROTEINS, LIPID CONSTITUENTS

INDEX

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