Chapter
Autoimmune therapeutic issues
Diabetes in childhood and adolescence
Diagnostic considerations
Management considerations
Main components of T1DM management
Management considerations
Genetic forms of diabetes
Diabetes mellitus and hyperlipidemia
Why screen, evaluate and manage pediatric hyperlipidemia?
Risk factors for ASCVD and hyperlipidemia
Physiology of lipid metabolism
Pathophysiology of atherosclerosis
Classification of hyperlipidemias
Primary causes of hyperlipidemias
Secondary causes of hyperlipidemia
Overweight/obesity/nutrition
Evaluation of hyperlipidemia in patients with diabetes mellitus
Physical exam (lipid deposition) findings
Management of hyperlipidemia
Dermatology and endocrinology
Diabetic cheiroarthropathy
Acanthosis nigricans (AN)
Scleredema adultorum of Buschke
Necrobiosis lipoidica diabetricorum (NLD)
Bullosis diabeticorum (BD)
Acquired perforating dermatosis (APD)
Nutrient deficiency dermatitis
Drug hypersensitivity reactions
Necrolytic migratory erythema (NME)
Familial atypical multiple mole melanoma-pancreatic cancer syndrome
Congenital malformations of the pancreas
2Department of Pediatric and Adolescent Medicine
3Department of Internal Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, US
Management considerations
Congenital adrenal hyperplasia (CAH)
Diagnostic considerations
CAH therapeutic management
Transition of care to adults
Section two: Behavioral issues
Coping and adaptation to a disability
Division of Developmental and Behavioral Pediatrics, Department of Pediatric and Adolescent Medicine, Western Michigan University, Homer Stryker, MD School of Medicine, Kalamazoo, Michigan, US
Adaptation – Focus on type 1 diabetes
Psychosocial adaptation and physiological adaptation
Common chronic illnesses and disabilities
Coping and adaptation to chronic illness and type 1 diabetes
Overarching concepts of coping and adaptation
Concepts of coping and adaptation
Child and adolescent developmental considerations
When to conduct psychosocial adaptation assessment
Assessment: Focus on type 1 diabetes
Treatment and intervention
Physician characteristics
Physician-patient relationship
Physician characteristics
Disability, chronic disease and death
Effects of dying on adolescent development
Issues with adolescent consent, accent, or refusal of treatment
Issues for health care professionals and hospital staff
Impending death of the teen patient
Management concepts for the hospital staff
Section three: Acknowledgments
About the Nationwide Children’s Hospital, Columbus, Ohio, United States
About the Department of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine (WMED), Kalamazoo, Michigan USA
About the National Institute of Child Health and Human Development in Israel
Service and academic activities
International collaborations
About the book series “Pediatrics, child and adolescent health”
Diabetes Mellitus: Childhood and Adolescence
( Pediatrics, Child and Adolescent Health (Series Editor: Joav Merrick - National Institute of Child Health and Human Development, Ministry of Social Affairs, Jerusalem) )
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