Author： Kudryavtsev Konstantin V. Irkha Veronika V.
Publisher： MDPI
E-ISSN： 1420-3049|10|7|755-761
ISSN： 1420-3049
Source： Molecules, Vol.10, Iss.7, 2005-08, pp. : 755-761
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Abstract
Tetrasubstituted pyrrolidines representing analogs of homoproline were synthesized by three-component condensation of aryl(heteroaryl)aldehydes, asparagine and N-methylmaleimide (NMM). Compounds with (1S*, 3R*, 3aS*, 6aR*)-configuration at the corresponding carbon positions of the bicyclic pyrrolidine ring could be isolated on a preparative scale.
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