Microwave-Assisted Synthesis of Substituted Hexahydro-pyrrolo[3,2-c]quinolines†

Author： Neuschl Michal   Bogdal Darek   Potacek Milan  

Publisher： MDPI

E-ISSN： 1420-3049|12|1|49-59

ISSN： 1420-3049

Source： Molecules, Vol.12, Iss.1, 2007-01, pp. : 49-59

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Abstract

New compounds with the ethyl hexahydro-1H-pyrrolo[3,2-c]quinoline-2-carboxylate skeleton were prepared by microwave-assisted intramolecular 1,3-dipolar cycloaddition reactions. The reactions were carried out under solvent-free conditions and compared with the same reaction in the presence of a solvent and a catalyst. Steric effects on the selectivity of the reaction were noted and evaluated.

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