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Open access

A New Tetrahydrofuran Lignan Diglycoside from Viola tianshanica Maxim

Author： Qin Yan Yin Chengle Cheng Zhihong

Publisher： MDPI

E-ISSN： 1420-3049|18|11|13636-13644

ISSN： 1420-3049

Source： Molecules, Vol.18, Iss.11, 2013-11, pp. : 13636-13644

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Abstract

A new lignan glycoside, tianshanoside A (1), together with a known phenylpropanoid glycoside, syringin (2) and two known lignan glycosides, picraquassioside C (3), and aketrilignoside B (4), were isolated from the whole plant of Viola tianshanica Maxim. The structure of the new compound was elucidated by extensive NMR (¹H, ¹³C, COSY, HSQC, HMBC and ROESY) and high resolution mass spectrometry analysis. The three lignans 1, 3, and 4 did not exhibit significant cytotoxicity against human gastric cancer Ags cells or HepG2 liver cancer cells. This is the first report of the isolation of a lignan skeleton from the genus Viola L.

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