Author: Bonaretti S Carpenter R D Saeed I Burghardt A J Yu L Bruesewitz M Khosla S Lang T
Publisher: IOP Publishing
E-ISSN: 1361-6560|59|24|7819-7834
ISSN: 0031-9155
Source: Physics in Medicine and Biology, Vol.59, Iss.24, 2014-12, pp. : 7819-7834
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Abstract
Quantitative computed tomography (QCT) is increasingly used in osteoporosis studies to assess volumetric bone mineral density (vBMD), bone quality and strength. However, QCT is confronted by technical issues in the clinical research setting, such as potentially confounding effects of body size on vBMD measurements and lack of standard approaches to scanner cross-calibration, which affects measurements of vBMD in multicenter settings. In this study, we addressed systematic inter-scanner differences and subject-dependent body size errors using a novel anthropomorphic hip phantom, containing a
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