Publisher: John Wiley & Sons Inc
E-ISSN: 1099-0690|2015|12|2678-2682
ISSN: 1434-193x
Source: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Vol.2015, Iss.12, 2015-04, pp. : 2678-2682
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
AbstractConditions for the palladium–NHC‐catalyzed amination of aryl sulfides with aliphatic as well as aromatic amines were established. The KHMDS‐mediated amination of heteroaryl sulfides could proceed without palladium. Based on the distinct difference in reactivity of C–Br and C–S bonds, a sequential amination of bromothioanisole can take place to install two different alkylamino groups onto the aromatic ring in one pot.