Publisher: John Wiley & Sons Inc
E-ISSN: 1616-3028|25|38|6147-6147
ISSN: 1616-301x
Source: ADVANCED FUNCTIONAL MATERIALS, Vol.25, Iss.38, 2015-10, pp. : 6147-6147
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Abstract
On page 6050, J. J. de Pablo and co‐workers demonstrate detection of Nanomolar concentrations of peptides by polarized light microscopy. Liquid crystals exhibit a specific response to beta‐sheet structures. The unstructured peptides involved in various diseases form beta‐sheet rich amyloid fibrils at lipid‐decorated liquid crystal interfaces, thereby altering the orientation of the underlying liquid crystal and yielding characteristic optical signatures that are interpreted in terms of detailed molecular models.
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