The normal white (w+) gene in Drosophila is required for production of red pigment in the eyes. In some mutants in which the w+ gene has been moved to a region near the centrosomal heterochromatin due to an inversion in the X chromosome, the eyes are mottled with red and white patches; the w+ gene in the white cells has been silenced due to spreading heterochromatin, while w+ gene in the red cells is active. This phenomenon is called PEV (position‐effect variegation), and a number of factors that control epigenetics, such as histone methyltransferases, have been identified by measuring the extent of variegation. Now, in this sliding screen, maple leaves in autumn were drawn with Japanese ink on gold foil background except some in the central oval with a red paint as an accent. A shadow that looks like Drosophila happened to be cast on it, emerging a figure of the w mutant with a mottled eye. Designed by TRAIS Co., Ltd. (Kobe, Japan)

Publisher： John Wiley & Sons Inc

E-ISSN： 1365-2443|20|11|i-i

ISSN： 1356-9597

Source： GENES TO CELLS, Vol.20, Iss.11, 2015-11, pp. : i-i

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