Chapter
Chapter 1 The need for engineering neural tissue using stem cells
1 Overview of the Nervous System
2 Demand for Cures for Neurodegenerative Diseases and Disorders Using Neural Tissue Engineering
2.4 Amyotrophic Lateral Sclerosis
2.6 Traumatic Brain Injury
2.7 Traumatic Spinal Cord Injury
3 The Discovery of Stem Cells and Their Impact on Tissue Engineering
4 The Need for Interdisciplinary Approaches for Treating Neurological Disorders
Chapter 2 Introduction to the nervous system
2 The Structure and Function of the Central Nervous System
3 Peripheral Nervous System
4 Cells of the Nervous System
4.5 Other Cells of the Nervous System
More Reading on History of Understanding Neuroanatomy Structure and Function
Resources Associated With Gross Neuroanatomy
Gray's Anatomy (Current and Original Editions)
Resources Associated With Cellular Level Neuroanatomy
Chapter 3 Stem cells and their applications in repairing the damaged nervous system
2 Discovery of Bone Marrow Stem Cells, Their Role in Nervous System, and Their Potential Applications in Treating the Dam ...
2.1 Discovery of Bone Marrow Stem Cells and Their Role in the Body
2.2 Application of Mesenchymal Stem Cell Therapies for Applications in the Nervous System
3 Discovery of Neural Stem Cells and Their Applications for Nervous System Repair
4 Derivation of Human Embryonic Stem Cells and Their Applications for Nervous System Repair
5 Derivation of Induced Pluripotent Stem Cells and Their Applications for Nervous System Repair
6 Direct Reprogramming of Mature Cells Into Functional Neural Cells
7 Concluding Remarks on Stem Cells and Their Potential as Cell Therapies
Chapter 4 Design considerations when engineering neural tissue from stem cells
2 Chemical Properties of Neural Tissue
2.1 Proteins of the Extracellular Matrix and Their Function
2.1.5 Glycoproteins found in the extracellular matrix of the nervous system
2.2 Polysaccharides Found in the Extracellular Matrix and Their Function
2.2.1 Hyaluronan/hyaluronic acid
2.2.2 Chondroitin sulfate
2.2.3 Heparin and heparan sulfate
2.2.4 Keratan sulfate/keratosulfate
2.3 Composition of the Extracellular Matrix of the Brain and the Spinal Cord
2.4 Composition of the Extracellular Matrix in the Peripheral Nervous System
2.5 Role of Growth Factors in the Extracellular Matrix
2.6 The Role of Small Molecules in Neuronal Development
3 Mechanical Properties of Neural Tissue
3.1 The Physical Topography of the Extracellular Matrix and Its Effect on Cellular Behavior
3.2 The Mechanical Properties of Neural Tissue and How They Relate to Stem Cell Behavior
4 Implications for Design of Biomaterial Scaffolds
Cell Biology Textbooks for Further Reading About the Extracellular Matrix
Textbooks About Biomaterials for Further Reading
Textbooks About Tissue Engineering for Further Reading
Companies That 3D Print Tissues
Chapter 5 Natural biomaterials for engineering neural tissue from stem cells
2.2.4 Methylcellulose and nitrocellulose
2.2.6 Hyaluronan/hyaluronic acid
2.3 Mixtures of the Different Natural Extracellular Matrix Components as Scaffolds for Controlling Stem Cell Behavior for ...
3 Decellularized Biomaterials
Links to Web Resources About Biomaterials
Textbooks About Biomaterials for Further Reading
Textbooks About Tissue Engineering for Further Reading
Chapter 6 Synthetic biomaterials for engineering neural tissue from stem cells
2 Types of Synthetic Scaffolds
2.1 Poly (Ethylene Glycol)/Poly (Ethylene Oxide)
2.2 Poly (Glycolic Acid)/Poly (Lactic Acid)/Poly (Lactic-co-glycolic Acid)
2.4 Poly (2-Hydroxyethyl Methacrylate)
2.6 Poly(dimethylsiloxane)
2.7 Self-Assembling Peptides
2.8 Other Potential Polymers Suitable for Applications in Neural Tissue Engineering Using Stem Cells
3 The Development of “Smart” Biomaterials That Respond to Stimuli
Link to the Chart Showing the Single Letter Abbreviations for Each Amino Acid
Links to Web Resources About Biomaterials
Textbooks About Biomaterials for Further Reading
Textbooks About Tissue Engineering for Further Reading
Chapter 7 Drug delivery systems for engineering neural tissue
2 Diffusion-Based Drug Delivery Systems
3 Affinity-Based Drug Delivery Systems
3.1 Heparin-Based Drug Delivery Systems
3.2 Other Types of Affinity-Based Drug Delivery Systems
4 Immobilization-Based Drug Delivery Systems
5 Electrically Controlled Drug Delivery Systems
6 Optically Controlled Drug Delivery Systems
Books Related to Drug Delivery
Chapter 8 New technologies for engineering neural tissue from stem cells
1 Introduction to New Technologies for Engineering Neural Tissues From Stem Cells
2 Generation of Neural Organoids From Stem Cells
3 The Use of 3D Bioprinting to Produce on Demand Neural Tissues
4 In Vitro and In Vivo Engineering of Neural Tissue From Somatic Cells
5 Genome Editing for Engineering Neural Tissue
6 Optogenetics and Designer Receptors Exclusively Activated by Designer Drugs (DREADDs)
Resources Related to 3D Bioprinting
Resources Related to Organoids
Resources Related to Direct Reprogramming of Cells
Resources Related to Gene Editing
Resources Related to Optogenetics and DREDDs
Engineering Neural Tissue from Stem Cells
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