Relation between lymphocyte to monocyte ratio and short‐term mortality in patients with acute pulmonary embolism

E-ISSN： 1752-699x|12|2|580-586

ISSN： 1752-6981

Source： THE CLINICAL RESPIRATORY JOURNAL, Vol.12, Iss.2, 2018-02, pp. : 580-586

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

IntroductionThe relationship between inflammation and mortality after acute pulmonary embolism (APE) has previously been investigated with different variables (platelet/lymphocyte ratio, etc).

ObjectivesWe investigated the predictive value of lymphocyte to monocyte ratio (LMR) for mortality in first 30 days after APE.

MethodsThe study population included 264 APE patients of which 230 patients were survivors, 34 patients were non‐survivors.

ResultsLMR was significantly lower in non‐survivors after APE (P < .001). Neutrophil‐to‐lymphocyte ratio (NLR) was higher in non‐survivors after APE (P < .001). Platelet‐to‐lymphocyte (PLR) had no significance between both groups (P: .241). Simplified pulmonary embolism severity index and LMR were independent predictors of mortality in patients with APE (P: .008 and P: .001, respectively).

ConclusionLMR as a novel marker of inflammation seemed to be an independent predictor of short‐term mortality in patients with APE.