Targeting cancer stem cells and signaling pathways by resveratrol and pterostilbene

E-ISSN： 1872-8081|44|1|61-68

ISSN： 0951-6433

Source： BIOFACTORS (ELECTRONIC), Vol.44, Iss.1, 2018-01, pp. : 61-68

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

AbstractIn past decades, increasing evidence regarding cancer stem cells (CSCs) may account for carcinogenesis, tumor drug‐resistant, and metastasis. CSCs are even considered as the root causes of tumor recurrence and metastases. Targeting CSCs may provide a new clue to cure cancer. Epidemiological and clinical studies have suggested that intake of dietary natural products may bring health benefits including lowering risk of cancer incidence. In this review, we have particularly focused on targeting signaling pathways of CSCs by natural resveratrol and its dimethylated derivative pterostilbene. © 2017 BioFactors, 44(1):61–68, 2018