Polymorphous Low-grade Adenocarcinoma of the Palate: Report of a Case and Review of Literature

Publisher: Jaypee Infomedia

E-ISSN: 0976–0539|2|1|57-60

ISSN: 0975-7899

Source: International Journal of Head and Neck Surgery, Vol.2, Iss.1, 2011-01, pp. : 57-60

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Abstract

ABSTRACTPolymorphous low-grade adenocarcinoma (PLGA) is a malignancy arising predominantly from minor salivary glands. PLGAs account for 10% of all tumors and 25% of all malignancies of the minor salivary glands. It has been frequently described as occurring in hard or soft palate minor salivary glands; some cases being described in the tongue and in major salivary glands. We report a case of PLGA of the palate extending into the maxillary sinus and nasal cavity diagnosed on the basis of histopathology and treated by subtotal maxillectomy. The review of literature concerning clinical, histological and immunohistochemical features, as well as the proper management concerning this tumor is included.