Dissociation constants of protolytic dissociation of glutamyl-glutamic and glycyl-glutamic acids in aqueous solution at 298 K

Author: Badelin V.  

Publisher: MAIK Nauka/Interperiodica

ISSN: 1070-3632

Source: Russian Journal of General Chemistry, Vol.83, Iss.5, 2013-05, pp. : 945-948

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Abstract

Protolytic dissociation constants of stepwise dissociation of glutamyl-glutamic and glycyl-glutamic acids in aqueous solutions at 298.15 K at ionic strengths of 0.1, 0.5, and 1.0 M on the NaCl background were measured by potentiometric titration. The thermodynamic dissociation constants were calculated. Using the obtained and published data, we discuss the effect of additional carboxy groups in the side chains of the molecule on the protolytic dissociation constants of peptides.

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