Author： Rémi Jan
Publisher： Springer Publishing Company
ISSN： 1617-6782
Source： Zeitschrift für Epileptologie, Vol.21, Iss.1, 2008-03, pp. : 2-5
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Abstract
Juvenile myoclonic epilepsy (JME) is a common epilepsy syndrome, well defined by its myoclonic seizures. Despite typical symptoms and EEG changes, JME is underdiagnosed and oftentimes inadequately treated with sodium channel blocking antiepileptic drugs (AEDs) like carbamazepine, oxcarbazepine and phenytoin. We have analyzed the treatment of 175 JME patients from our epilepsy service. Upon first presentation to our clinic, 42 patients (24%) were treated with sodium channel blocking AEDs, of whom only one patient was seizure free. After changing the therapy to mostly valproic acid or lamotrigine, 42% of these patients were seizure free. These numbers underline the importance of the syndrome diagnosis and an adequate AED choice in treating JME.
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