New Molecular Bioassays for the Estimation of the Teratogenic Potency of Valproic Acid Derivatives in Vitro: Activation of the Peroxisomal Proliferator-Activated Receptor (PPAR )

Author： Lampen A.   Siehler S.   Ellerbeck U.   Gottlicher M.   Nau H.  

Publisher： Elsevier

ISSN： 0041-008X

Source： Toxicology and Applied Pharmacology, Vol.160, Iss.3, 1999-11, pp. : 238-249

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Molecular modelling of the rat peroxisome proliferator-activated receptor - (rPPAR ) by homology with the human retinoic acid X receptor (hRXR ) and investigation of ligand binding interactions I: QSARs

By Lewis D.F.V.   Lake B.G.  

Toxicology in Vitro, Vol. 12, Iss. 6, 1998-12 ,pp. : 619-632

Elsevier

Access to resources Recommend Favorite

Molecular modelling of the peroxisome proliferator-activated receptor (PPAR ) from human, rat and mouse, based on homology with the human PPAR crystal structure

By Lewis D.F.V.   Jacobs M.N.   Dickins M.   Lake B.G.  

Toxicology in Vitro, Vol. 16, Iss. 3, 2002-06 ,pp. : 275-280

Elsevier

Access to resources Recommend Favorite

Cell Proliferation, Migration and CAM-dependent Neurite Outgrowth as Developmental In Vitro Endpoints for Screening Teratogenic Potential: Application to Valproic Acid and Related Analogues of Varying Potency

By Bacon C.L.   Berezin V.   Bode G.   Bock E.   Bojic U.   Doherty P.   Ehlers K.   Ellerbeck U.   Julien P.   Kawa A.   Maar T.E.   Nau H.   Pirovano R.   Regan C.M.   Schousboe A.   Spezia F.   Walsh F.S.   Williams E.J.  

Toxicology in Vitro, Vol. 12, Iss. 2, 1998-04 ,pp. : 101-109

Elsevier

Access to resources Recommend Favorite

Teratogenic Potency of Valproate Analogues Evaluated by Quantitative Estimation of Cellular Morphology In Vitro

By Berezin V.   Kawa A.   Bojic U.   Foley A.   Nau H.   Regan C.   Edvardsen K.   Bock E.  

Toxicology in Vitro, Vol. 10, Iss. 5, 1996-10 ,pp. : 585-594

Elsevier

Access to resources Recommend Favorite

Quantitative Structure-Activity Relationship (QSAR) Analysis for a Series of Rodent Peroxisome Proliferators: Interaction with the Mouse Liver Peroxisome Proliferator-activated Receptor (mPPAR )

By Lewis D.F.V.   Lake B.G.  

Toxicology in Vitro, Vol. 11, Iss. 1, 1997-02 ,pp. : 99-105

Elsevier

Access to resources Recommend Favorite