Chemical Modifications in Aggregates of Recombinant Human Insulin Induced by Metal-Catalyzed Oxidation: Covalent Cross-Linking via Michael Addition to Tyrosine Oxidation Products

Author: Torosantucci Riccardo  

Publisher: Springer Publishing Company

ISSN: 0724-8741

Source: Pharmaceutical Research, Vol.29, Iss.8, 2012-08, pp. : 2276-2293

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Abstract