Auditory event-related potentials in patients with psychotic illness: A 5-year follow-up

ISSN： 1355-4794

Source： Neurocase, Vol.18, Iss.5, 2012-10, pp. : 392-399

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Abstract

The auditory processing is diversely impaired in patients with the first-episode psychosis. During acute phase we previously reported reduced amplitudes in attention-dependent auditory evoked electrical brain potentials but not in those of early automatic components. Here seven first-episode patients at the disease onset and 5 years later were studied and compared to control subjects. At follow-up, also the unattended auditory stimuli elicited reduced amplitudes both in primary sensory component (N100, p</i> = .043) and in automatic deviance detection (N200, p</i> = .013) as compared to acute phase. Patients' psychopathology had improved, however they still showed alterations in components detecting automatic stimulus classification which may convey persisting tendency for misinterpretation in auditory perception.