Author： Seenivasagam R.
Publisher： Inderscience Publishers
ISSN： 1756-2104
Source： International Journal of Functional Informatics and Personalised Medicine, Vol.3, Iss.3, 2010-03, pp. : 204-214
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
The main objectives of the investigational study are in-vitro and in-vivo evaluation of Metformin Hcl tablets on Non-Insulin Dependent Diabetic Mellitus (NIDDM). Various tablet parameters were evaluated through in-vitro tests on marketed brands of Metformin Hcl tablets. The results obtained earlier are correlated with variation in dissolution profiles the dissolution profiles of the marketed brands with regard to any possible bio-equivalence are analysed. In-silico studies are important to locate molecular targets for NIDDM. Through homology modelling and active-site prediction, the suitable protein and receptor for Metformin Hcl were identified.
Related content
Access to resources
Recommend
