Use of combinatorial mutagenesis to select for multiply substituted human interleukin-3 variants with improved pharmacologic properties - insights from the interfacial and thermodynamic properties of hydrocarbons

Author： Klein B.K.   Olins P.O.   Bauer S.C.   Caparon M.H.   Easton A.M.   Braford S.R.   Abrams M.A.   Klover J.A.   Paik K.   Thomas J.W.   Hood W.F.   Shieh J.-J.   Polazzi J.O.   Donnelly A.M.   Zeng D.L.   Welply J.K.   McKearn J.P.  

Publisher： Elsevier

ISSN： 0301-472X

Source： Experimental Hematology, Vol.27, Iss.12, 1999-12, pp. : 1746-1756

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