Troubleshooting problems with in vitro screening of drugs for QT interval prolongation using HERG K + channels expressed in mammalian cell lines and Xenopus oocytes

Author: Witchel H.J.   Milnes J.T.   Mitcheson J.S.   Hancox J.C.  

Publisher: Elsevier

ISSN: 1056-8719

Source: Journal of Pharmacological and Toxicological Methods, Vol.48, Iss.2, 2002-09, pp. : 65-80

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Abstract