Antibacterial constituents from Stemona sessilifolia

Author: Zhang Tong   Zhang Ya-Zhong   Tao Jian-Sheng  

Publisher: Taylor & Francis Ltd

ISSN: 1028-6020

Source: Journal of Asian Natural Products Research, Vol.9, Iss.5, 2007-07, pp. : 479-485

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Abstract

Bioassay-guided fractionation led to the isolation of eight compounds from Stemona sessilifolia. Of the eight isolates, three new bibenzyls, stilbostemins M-O (1-3), and a new tocopherol, 6-methoxy-3,4-dehydro--tocopherol (4) were revealed together with four known compounds 3,5-dihydroxy-2'-methoxy bibenzyl (5), 3,5-dihydroxy bibenzyl (6), -tocopherol (7), and -tocopherol (8). Compounds 5, 6, and 8 exhibited strong antibacterial activities against Staphylococcus aureus and S. epidermidis.