Author： Vargas Franklin Rivas Carlos
Publisher： Taylor & Francis Ltd
ISSN： 1091-7659
Source： Toxic Substance Mechanisms, Vol.16, Iss.1, 1997-01, pp. : 81-86
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
Recent research on elucidation of mechanisms of the phototoxic activities of various pharmaceutical products currently being investigated in this laboratory is reviewed. Due to the importance of antibacterial quinolones of com mon use in present m edical practice, it is considered of general interest to summ arize the photochem ical reactions involved in the generation of active photoproducts and the possibility of metabolite mediation in biological damage. Thus, m echanism s are postulated for the photochemical decomposition of the substances investigated as well as the possible in vitro m echanism involved at cellular level.
Related content
Access to resources
Recommend
Apoptotic photoreceptor cell death induced by quinolone phototoxicity in mice
Toxicology Letters, Vol. 105, Iss. 1, 1999-03 ,pp. :