Minocycline inhibits cell death and decreases mutant Huntingtin aggregation by targeting Apaf-1

By Sancho Mónica   Herrera Andrés E.   Gortat Anna   Carbajo Rodrigo J.   Pineda-Lucena Antonio   Orzáez Mar   Pérez-Payá Enrique  

Human Molecular Genetics, Vol. 20, Iss. 18, 2011-09 ,pp. : 3545-3553

Oxford University Press

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IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux

By Lee Huikyong   Noh Jee-Yeon   Oh Yumin   Kim Youngdoo   Chang Jae-Woong   Chung Chul-Woong   Lee Soon-Tae   Kim Manho   Ryu Hoon   Jung Yong-Keun  

Human Molecular Genetics, Vol. 21, Iss. 1, 2012-01 ,pp. : 101-114

Oxford University Press

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Premature death and neurologic abnormalities in transgenic mice expressing a mutant huntingtin exon-2 fragment

By Tebbenkamp Andrew T.N.   Swing Debbie   Tessarollo Lino   Borchelt David R.  

Human Molecular Genetics, Vol. 20, Iss. 8, 2011-04 ,pp. : 1633-1642

Oxford University Press

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Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis

By Tanwar Pradeep S.   Kaneko-Tarui Tomoko   Zhang LiHua   Teixeira Jose M.  

Human Molecular Genetics, Vol. 21, Iss. 20, 2012-10 ,pp. : 4394-4405

Oxford University Press

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Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons

By Zala Diana   Colin Emilie   Rangone Hlne   Liot Graldine   Humbert Sandrine   Saudou Frdric  

Human Molecular Genetics, Vol. 17, Iss. 24, 2008-12 ,pp. : 3837-3846

Oxford University Press

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