Ataxin-3 with an altered conformation that exposes the polyglutamine domain is associated with the nuclear matrix

By Perez Matthew K.   Paulson Henry L.   Pittman Randall N.  

Human Molecular Genetics, Vol. 8, Iss. 13, 1999-12 ,pp. : 2377-2385

Oxford University Press

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The MachadoJoseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability

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Proteotoxic stress increases nuclear localization of ataxin-3

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Ataxin-3 is transported into the nucleus and associates with the nuclear matrix

By Tait D.  

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Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3

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